Search for dissertations about: "Glutathione Transferases"

Showing result 11 - 15 of 59 swedish dissertations containing the words Glutathione Transferases.

  2. 11. Catalysis by theta-class glutathione transferases : Substrate binding, product formation and product release

    Author : Per Jemth; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

    Abstract : Glutathione transferases (GSTs) are detoxication enzymes that catalyze theconjugation of glutathione to a large number of electrophilic molecules. In this waythey help to rid cells of potentially toxic substances. This thesis deals with thecatalysis afforded by Theta-class glutathione transferases. READ MORE

  4. 12. Microsomal glutathione transferase

    Author : Ralf Morgenstern; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : A distinct glutathione transferase which can be activated up to eightfold by sulfhydryl reagents was discovered in rat liver microsomes. This enzyme was subsequently purified to apparent homogeneity in 40 % yield using column cromatography. READ MORE

  5. 13. Glutathione transferases : markers for renal disease

    Author : Anders Sundberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Glutathione transferases (GST) alpha and pi were purified to homogeneity and used to develop immunochemical methods for analysis of the amount of these proteins in human urine. The methods were employed for diagnosis of renal dysfunctions caused by drugs and industrial chemicals. READ MORE

  6. 14. Alpha-class Glutathione Transferases from Pig: a Comparative Study

    Author : Natalia Fedulova; Bengt Mannervik; Francoise Raffalli-Mathieu; Mario Lo Bello; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; glutathione transferase; substrate selectivity; steroidogenesis; Sus scrofa; functional comparison; irreproducibility; reproducible assays; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Abstract : Glutathione transferases (GSTs, EC 2.5.1.18) possess multiple functions and have potential applications in biotechnology. READ MORE

  7. 15. Exploring the steroidogenic activity of glutathione transferases across species

    Author : Helena Lindström; Bengt Mannervik; Kjell Wikvall; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Glutathione transferase; steroidogenesis; GST A3-3; testis; androstenedione; pregnenedione; equine; steroidogenesis inhibition; Drosophila GSTE14; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Glutathione transferases (GSTs) comprise a superfamily of enzymes prominently involved in detoxication. However, some GSTs have developed alternative functions. READ MORE