Search for dissertations about: "Glutathione-S-transferases"
Showing result 1 - 5 of 6 swedish dissertations containing the word Glutathione-S-transferases.
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1. The significance of glutathione S-transferases in biochemical toxicology : kinetic and binding studies designed to establish a mechanism of action of glutathione S-transferase A from rat liver
Abstract : .... READ MORE
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2. Isolation and characterization of glutathione S-transferases from various animal sources
Abstract : In the present investigation several forms of glutathione S-transferase were found in preparations of rat liver, rat lung, adult human liver, fetal human liver and whole earthworms. Human placenta, however, appeared to contain only one form of glutathione S-transferase. READ MORE
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3. Oxidative damage and the DNA glycosylase MutYH
Abstract : The DNA glycosylase MutYH is highly conserved throughout evolution, and homologs are found in most eukaryotes and prokaryotes examined. MutYH functions as a base excision repair DNA glycosylase that excises adenines misincorporated opposite 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG), one of the most stable products of oxidative DNA damage. READ MORE
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4. Identification of arachidonic acid metabolites formed through the 15-lipoxygenase-1 pathway
Abstract : The polyunsaturated fatty acid arachidonic acid is the precursor of many biologically active lipid mediators. This thesis is focused on the arachidonic acid metabolites formed through the 15-lipoxygenase-1 (15-LO-1) pathway. READ MORE
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5. Biochemical properties of human glutaredoxins
Abstract : Glutaredoxins (Grxs) are highly conserved thiol-disulfide oxidoreductases that utilize electrons from the tripeptide glutathione (GSH) to catalyze thiol-disulfide exchange reactions. Bacteria, yeast and plants contain multiple dithiol Grxs, which are involved in different cellular processes like DNA synthesis, defense against oxidative stress, apoptosis, and regulation of transcription factor binding activity. READ MORE