Search for dissertations about: "Glycoconjugates"
Showing result 1 - 5 of 34 swedish dissertations containing the word Glycoconjugates.
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1. Glycoconjugates : synthesis and investigation of carbohydrate-protein interactions
Abstract : To study the functions of glycoconjugates in biological systems reliable and efficient protocols for glycoconjugate synthesis are needed. To reach this goal we have developed methods for solid-phase synthesis of glycoconjugates that can be monitored with gel-phase 19F spectroscopy using fluorinated linkers, building blocks, and protecting groups. READ MORE
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2. Glycoconjugates : Solid-phase synthesis and biological applications
Abstract : Glycoconjugates are biologically important molecules with diverse functions. They consist of carbohydrates of varying size and complexity, attached to a non-sugar moiety as a lipid or a protein. Glycoconjugate structures are often very complex and their intricate biosynthetic pathways makes overexpression difficult. READ MORE
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3. Carbohydrate-Based Inhibitors of Pathogen Adhesion to Cell Surface Glycoconjugates
Abstract : The fact that a growing number of pathogens develop resistance against traditional treatment is a growing medical problem. Infections, which until now have been harmless, might turn into life threatening diseases. These problems have led to an intensified search for alternative treatments. Analogs of cell surface glycoconjugates are an alternative. READ MORE
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4. Conformational, dynamics and interaction studies of glycoconjugates by NMR spectroscopy
Abstract : .... READ MORE
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5. Design and Synthesis of Sialic Acid Conjugates as Inhibitors of EKC-causing Adenoviruses
Abstract : The combat against viral diseases has been, and still is, a major challenge in the field of drug development. Viruses are intracellular parasites that use the host cell ma-chinery for their replication and release. Therefore it is difficult to target and destroy the viral particle without disturbing the essential functions of the host cell. READ MORE