Search for dissertations about: "Glycogen storage disease"
Found 5 swedish dissertations containing the words Glycogen storage disease.
-
1. Human glycogen synthase genes. Role in insulin resistance and hypoglycaemia
Abstract : Effective insulin-stimulated storage of excess glucose after a meal, and its rapid mobilisation in the fasting state provide basis of glucose homeostasis. Glycogen is the macromolecular storage form of glucose and glycogen synthase (GS) is the rate-limiting enzyme in glycogen synthesis. Skeletal muscle and liver are the major depots of glycogen. READ MORE
-
2. Two new disorders of glycogen metabolism
Abstract : Glycogen is a polymer of glucose and serves as a source of rapidly available energy. Glycogen synthesis is initiated by autoglucosylation of glycogenin. Two glycogenin genes, GYG1 and GYG2, encode the two isoforms glycogenin-1 and -2, respectively. READ MORE
-
3. Crisis in Energy Metabolism - Mitochondrial Defects and a New Disease Entity
Abstract : Impairment of energy metabolism may be associated with severe implications for affected individuals since all fundamental cell functions are energy-dependent. Disorders of energy metabolism are often genetic and associated with defects in the oxidative phosphorylation in mitochondria. READ MORE
-
4. Pathways controlling metabolic and hypertrophic responses in skeletal muscle
Abstract : Skeletal muscle displays an extensive capacity to adapt to a wide range of metabolic and mechanical stressors. As an insulin-sensitive and exercise-responding tissue, it plays a key role in the context of therapeutic interventions targeting metabolic diseases including type 2 diabetes (T2D) and obesity. READ MORE
-
5. Functional and metabolic alterations in skeletal muscle in response to physiological and pathophysiological stressors
Abstract : Skeletal muscle performance is essential for our body’s movement as well as for the wholebody metabolism. In health and disease, skeletal muscle is exposed to various endogenous and exogenous stressors, influencing its physiological functions. READ MORE