Search for dissertations about: "Glycosylation"

Showing result 11 - 15 of 192 swedish dissertations containing the word Glycosylation.

  1. 11. Infectious Pancreatic Necrosis Virus (IPNV) - Structural Studies and Methodology

    Author : Linda Eliasson; Molekylär cellbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; Microbiology; VP2; Glycosylation; Immuno dot blot; IPNV; TCID50;

    Abstract : Infectious pancreatic necrosis virus (IPNV) is a Birnavirus that infects salmonid fish. The infection is usually mortal for fish under six months of age, while older fish become carriers, usually without any signs of infection, and will spread the virus to other susceptible fish and to their offspring. READ MORE

  2. 12. Helicobacter spp. – host interaction in the mucus niche

    Author : Médea Padra; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter; mucin; glycosylation; adhesion;

    Abstract : Helicobacter pylori is the most common human gastric pathogen, colonizing half of the world's population. Helicobacter suis colonizes the stomach of 60-95% of pigs at slaughter age and it is the most prevalent non-Helicobacter pylori Helicobacter species found in the human stomach causing severe gastric disorders. READ MORE

  3. 13. Development and Application of Proximity Assays for Proteome Analysis in Medicine

    Author : Felipe Marques Souza de Oliveira; Masood Kamali-Moghaddam; Ulf Landegren; Mats Gullberg; Janne Lehtiö; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Solid-phase proximity ligation assay; post-translational modifications; glycosylation; phosphorylation; Enzyme-linked immunosorbent assay; immunoassay and rolling circle amplification; Proximity Extension Assay; inflammation protein biomarkers; autoantibodies; autoimmune disease;

    Abstract : Along with proteins, a myriad of different molecular biomarkers, such as post-translational modifications and autoantibodies, could be used in an attempt to improve disease detection and progression. In this thesis, I build on several iterations of the proximity ligation assay to develop and apply new adaptable methods to facilitate detection of proteins, autoantibodies and post-translational modifications. READ MORE

  4. 14. Intrapatient evolution of HIV-1 in the context of coreceptor usage

    Author : Mattias Mild; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coreceptor switch; Medicine human and vertebrates ; Medicin människa och djur ; biological cloning; R5-X4; coreceptor usage; glycosylation; recombination; HIV; evolution;

    Abstract : The variable region 1 to 3 (V1-V3) of the HIV-1 envelope plays an important role in coreceptor usage. Early in infection HIV- 1 is using CCR5 as coreceptor to enter target cells (R5 viruses) whereas viruses using CXCR4 as coreceptor (X4 viruses) may appear later in infection. READ MORE

  5. 15. Clusterin in brain and cerebrospinal fluidin Alzheimer s disease

    Author : Anna-Maria Nilselid; Göteborgs universitet; []
    Keywords : Alzheimer s disease; clusterin; apolipoprotein J; SP-40; brain tissue; cerebrospinal fluid; glycosylation; biomarker; enzyme-linked immunosorbent assay;

    Abstract : The apolipoprotein clusterin is suggested to be involved in the pathogenesis of Alzheimer¡¦s disease (AD). At the start of these studies, results had indicated that clusterin was elevated in AD brain, compared with controls. READ MORE