Search for dissertations about: "Growth-hormone"

Showing result 1 - 5 of 178 swedish dissertations containing the word Growth-hormone.

  1. 1. Growth Hormone in Athletes

    Author : Christer Ehrnborg; Göteborgs universitet; []
    Keywords : Growth hormone; IGF-I; bone markers; doping; athletes; maximum exercise test; variability; supraphysiological; body composition; physical performance; IGFBP-4; IGFBP-5;

    Abstract : Doping with growth hormone (GH) is a well-known problem both among elite athletes and among people training at gyms. It is mainly the anabolic and, to some extent, lipolytic effect of GH that is valued by its users. READ MORE

  2. 2. Cardiovascular effects of growth hormone, IGF-I and growth hormone secretagogues

    Author : Åsa Tivesten; Göteborgs universitet; []
    Keywords : cardiovascular system; growth hormone; insulin-like growth factor-I; growth hormone secretagogues; echocardiography.;

    Abstract : Growth hormone (GH) may exert direct growth-promoting and metabolic actions on target tissues, but most of its effects are mediated by circulating (endocrine) or local (auto-/paracrine) insulin-like growth factor-I (IGF-I). The GH/IGF-I system has an important role during cardiac development and for maintaining the structure and function of the heart. READ MORE

  3. 3. Identification of novel growth hormone-regulated factors

    Author : Björn Andersson; Göteborgs universitet; []
    Keywords : Growth hormone; idiopathic short stature; growth hormone deficient; prepubertal; children; genomic; proteomic;

    Abstract : The studies described in this thesis aimed to identify novel factors involved in the regulation of longitudinal growth and bone mineralization in response to growth hormone (GH) treatment. This was done by performing a single factor study (Paper I) where it was found that growth response was negatively correlated with adiponectin levels during the first year of GH treatment in short prepubertal children. READ MORE

  4. 4. Growth hormone in the brain : Focus on cognitive function

    Author : Erika Brolin; Fred Nyberg; Mathias Hallberg; Alfhild Grönbladh; Jörgen Isgaard; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Growth hormone; central nervous system; cognition; morphine; gamma-hydroxybutyrate; diabetes; Barnes maze; Morris water maze; mice; rats; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Cognitive impairments are an increasing health problem worldwide. In the developed countries, the average life expectancy has dramatically increased over the last decades, and with an elderly population more cases of cognitive impairments appear. READ MORE

  5. 5. Growth hormone responsiveness in children : results from Swedish multicenter clinical trials of growth hormone treatment

    Author : Elena Lundberg; Berit Kriström; Kerstin Albertsson-Wikland; Roland Pfäffle; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gain in height; puberty; IGHD; non-GHD; IGF-I; bioavailability;

    Abstract : The general aims of the thesis were to study GH responsiveness by estimation of pharmacokinetics and bioavailability of injected recombinant human GH (rhGH), of growth response as gain in heightSDS during childhood and puberty, and IGF-I response as change in circulating IGF-ISDS and IGFBP3SDS. Methods Short children were recruited during 1988–1999 into two national randomized multicentre clinical trials on growth until adult height. READ MORE