Search for dissertations about: "Guanidine"

Showing result 1 - 5 of 10 swedish dissertations containing the word Guanidine.

  2. 1. Biophysical Studies of Apolipoprotein A-IM and a Partitioning study

    Author : Malin Suurkuusk; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Apolipoprotein A-IMilano; Apolipoprotein A-I; Lipoprotein; Lipid; Microcalorimetry; DCS; Denaturation; Guanidine Hydrochloride; Physics; Fysik; Chemistry; Kemi;

    Abstract : The major part of this thesis deals with the similarities and differences in some biophysical properties of apolipoprotein A-I (apo A-I) and the molecular variant apolipoprotein A-IMilano (apo A-IM), and the influence on lipid binding. A model compound partitioning study has also been performed. READ MORE

  4. 2. Investigations of New Biomimetic Transamination Systems and Inclusion Complexation with Cyclodextrins

    Author : Anders Hjelmencrantz; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; stereochemis; bicyclooctanes.Transamination; complexation; cyclodextrins; proton transfer; hydride transfer; stereochemistry; Transamination; Organic chemistry; Organisk kemi;

    Abstract : Two new transamination systems are described. The first example is a dibenzo[a,d]- cycloheptene containing system, designed to accomplish a [1,3]-hydride transfer. Several catalysts have been examined for this purpose. tris-Pentafluorophenyl borane was found to be the most efficient catalyst. READ MORE

  5. 3. Discovery of N-hydroxyguanidines as novel electron acceptors of xanthine oxidase : Potential new drugs for treatment of ischemia and reperfusion injury

    Author : Maija Dambrova; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; xanthine oxidase; N-hydroxyguanidine derivatives; ischemia and reperfusion; reduction; inhibition; superoxide; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; galenisk farmaci; Pharmaceutics;

    Abstract : Xanthine oxidase (EC 1.1.3.22) is one of the major enzymatic sources of oxygen-derived free radicals. READ MORE

  6. 4. From Macromolecular Design to Supramolecular Self-assembly

    Author : Lidija Glavas; Ann-Christine Albertsson; Karin Odelius; Matthew Becker; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Self-assembly; micelles; core crystallinity; cyclic polypeptides; electroactivity; redox-responsiveness; triggered dissociation; loading; release; N-carboxyanhydride polymerization; polyesters; poly ε-decalactone ; Självorganisation; miceller; kärnkristallinitet; cykliska polypeptider; elektroaktivitet; tidsberoende dissociation; inkapsling; frisläppning; N-karboxyanhydrid polymerisation; polyestrar; poly ε-dekalakton ; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Abstract : Advancements in drug delivery have enabled a wider array of prevention, control and treatment of diseases such as cancer. Drug delivery systems have the possibility of encapsulating drugs with low solubility, delivering them to specific locations in the body as well as obtaining a controlled and sustained drug release. READ MORE

  7. 5. Selective Transformations of Allylic Compounds and Enol Derivatives : Synthesis of Fluorinated and Nitrogenated Scaffolds

    Author : Víctor García-Vázquez; Belén Martín‐Matute; Mario Waser; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Fluorinated compounds; Base catalysis; Ion-Pair; Isomerization; Pd catalysis; Method development; Hypervalent iodine III ; Organic Chemistry; organisk kemi;

    Abstract : In this thesis, new synthetic methods to give access to molecules having fluorinated scaffolds and other polar functional groups have been developed. The methods give access to highly valuable organic compounds that may serve as building blocks in the synthesis of functionalized drug candidates. READ MORE