Search for dissertations about: "Guilherme de Araújo Lucas"

Found 1 swedish dissertation containing the words Guilherme de Araújo Lucas.

2. 1. On cholecystokinin-opioid interaction in the spinal dorsal horn following peripheral nerve injury and inflammation

   Author : Guilherme de Araújo Lucas; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Cholecystokinin; Cholecystokinin receptors; Morphine; Spinal cord; Axotomy; Inflammation; Peptide release; Morphine tolerance; [my]-opioid receptor; Flexor reflex; Microdialysis;

   Abstract : The peptide cholecystokinin (CCK) antagonizes opioid-induced analgesia. Conversely, antagonists of CCK receptors enhance the analgesic effect of opioids. Together, these results support a role for CCK as an anti-opioid peptide in pain mechanisms. READ MORE