Search for dissertations about: "Gunilla Enblad"

Showing result 11 - 15 of 26 swedish dissertations containing the words Gunilla Enblad.

  2. 11. Immunologic Markers in the Tumor Microenvironment of Classical Hodgkin Lymphoma

    Author : Alex R. Gholiha; Gunilla Enblad; Rose-Marie Amini; Peter Hollander; Gustaf Hedström; Arjan Diepstra; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tumor microenvironment; immunohistochemistry; immune checkpoints; Plasma cells; IL-6 cytokine; Proteomics; CD47.;

    Abstract : In classical Hodgkin lymphoma (cHL), cytokine regulation and cellular composition of the tumor microenvironment (TME) is crucial for tumor cell survival. In paper I, we examined the presence of CD138+ plasma cells and IgG4+ plasma cells in diagnostic cHL biopsies with immunohistochemistry (IHC). READ MORE

  4. 12. Hodgkin Lymphoma – an Interplay Between Tumour Cell and Microenvironment

    Author : Ingrid Glimelius; Gunilla Enblad; Daniel Molin; Rose-Marie Amini; Marie Fischer; Volker Diehl; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN; Oncology; onkologi;

    Abstract : Hodgkin lymphoma (HL) is a malignant disorder characterised by few tumour cells surrounded by a massive infiltrate of inflammatory cells, fibrosis, and microvessels. Therefore, it is a good model in which to study the interplay between tumour cells and the microenvironment. READ MORE

  5. 13. Prognostic Markers in Diffuse Large B-cell Lymphoma : How Bad can it be

    Author : Gustaf Hedström; Gunilla Enblad; Francesco D'Amore; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; DLBCL; Survival; Mast cell; Microenvironment; MicroRNA; MDM2; Polymorphism; Age; Epidemiology; Oncology; Onkologi;

    Abstract : Diffuse large B-cell lymphoma (DLBCL), which is the most common type of lymphoma, is characterised by its aggressiveness and poor outcome without adequate treatment and also for its biological and clinical heterogeneity. It is therefore highly desirable to gain a more profound understanding of the underlying biology of the disease, as well as predictive factors for the guidance of treatment. READ MORE

  6. 14. The clinical perspective on malignancies in renal transplanted patients

    Author : Vivan Hellström; Tomas Lorant; Gunnar Tufveson; Gunilla Enblad; Per Lindnér; Uppsala universitet; []
    Keywords : renal transplantation; malignant tumours;

    Abstract : Post-transplant malignancies cause significant morbidity and mortality. In this thesis we investigated malignancies in renal transplanted patients from a clinical viewpoint. The use of regional tumour registries considerably improved identification of pre- and post-transplant malignancies, which are generally underreported in transplant registries. READ MORE

  7. 15. Epidemiology and prognosis in classical Hodgkin lymphoma

    Author : Peter Hollander; Ingrid Glimelius; Rose-Marie Amini; Gunilla Enblad; Lydia Visser; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; rheumatoid arthritis; tumor microenvironment; immunohistochemistry; immune checkpoints; regulatory T lymphocytes; PD-1; PD-L1; Oncology; Onkologi; Patologi; Pathology;

    Abstract : Classical Hodgkin lymphoma (HL) is a B cell derived neoplasm with an overall good prognosis. Its etiology and pathogenesis are largely unknown. The tumor microenvironment consists of sparse malignant cells and abundant leukocytes. READ MORE