Search for dissertations about: "Gunnar Boysen"

Found 2 swedish dissertations containing the words Gunnar Boysen.

  2. 1. Development of an adductomic approach to identify electrophiles in vivo through their hemoglobin adducts

    Author : Henrik Carlsson; Margareta Törnqvist; Gunnar Boysen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Adductomics; Hemoglobin adducts; LC MS MS; Ethyl vinyl ketone; Glyoxal; Methylglyoxal; Acrylic acid; 1-Octen-3-one; Environmental Chemistry; miljökemi;

    Abstract : Humans are exposed to electrophilically reactive compounds, both formed endogenously and from exogenous exposure. Such compounds could react and form stable reaction products, adducts, at nucleophilic sites in proteins and DNA. READ MORE

  4. 2. DNA adductomics: Method development and integration in biological effect monitoring

    Author : Giulia Martella; Elena Gorokhova; Hitesh V. Motwani; Brita Sundelin; Gunnar Boysen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA adducts; Nucleic acids; High-resolution mass spectrometry; Data-independent acquisition; Biological effect monitoring; Environmental contaminants; Biomarkers; Amphipods as sentinel species; Environmental Sciences; miljövetenskap;

    Abstract : Environmental omics can provide informative biomarkers for identifying pathologies or physiological responses to environmental change. Nucleic acid adductomics, one of the newest omics techniques, is particularly well suited for assessing exposure and effects of environmental contaminants because the technique can capture modifications at the (epi)genome level. READ MORE