Search for dissertations about: "Gunnar Thorsen"
Found 3 swedish dissertations containing the words Gunnar Thorsen.
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1. Micellar electrokinetic chromatography with laser-induced fluorescence detection applied to the analysis of biological samples
Abstract : The research presented in this thesis is focused on the potential for using the combination of micellar electrokinetic chromatography with laser-induced fluorescence detection for the determination of compounds in biological samples. The topics that have been addressed are the development of separation electrolytes, the need for sample preparation procedures, the derivatization of the compounds of interest and the detection of these by laser-induced fluorescence. READ MORE
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2. Novel Solid Phase Extraction and Mass Spectrometry Approaches to Multicomponent Analyses in Complex Matrices
Abstract : Analysis of compounds present in complex matrices is always a challenge, which can be partly overcome by applying various sample preparation techniques prior to detection. Ideally, the extraction techniques should be as selective as possible, to minimize the concentration of interfering substances. READ MORE
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3. Compact-disc microfluidic methods for characterization of therapeutic antibodies : Analysis of post-translational modifications
Abstract : Characterization of post-translational modifications (PTMs) of therapeutic proteins is very important during the bioprocess development to maintain desired product quality and during the submission process to regulatory authorities for product approval. Monitoring glycosylation in pharmacokinetic studies can be useful to evaluate the dependence of clearance rates on different glycoforms. READ MORE