Search for dissertations about: "Gunnel Hallden"

Found 2 swedish dissertations containing the words Gunnel Hallden.

2. 1. Adenovirus-mediated Gene Therapy of Prostate Cancer

   Author : Angelika Danielsson; Mangus Essand; Thomas H. Tötterman; Gunnel Hallden; Uppsala universitet; []
   Keywords : adenovirus; adenoviral vector; oncolytic virus; gene therapy; prostate cancer; PEGylation; HDAC inhibitor; whole blood model; whole blood neutralization assay; MEDICINE; MEDICIN; Klinisk immunologi; Clinical Immunology; Molekylär genetik; Molecular Genetics;

   Abstract : Adenovirus-mediated gene therapy is a potential complement to standard cancer treatments. Advantages are that vectors can be used to target tumors and that replicating viruses lead to increased therapeutic dosage. READ MORE

4. 2. Replication-competent adenovirus 11p vector as a new oncolytic agent

   Author : Jim Silver; Ya-Fang Mei; Gunnel Halldén; Umeå universitet; []
   Keywords : Virologi; Adenovirus; Vector; mikrobiologi; Microbiology;

   Abstract : Human adenoviruses (Ads) as vectors have been studied for cancer gene therapy for several decades due to their ability to shut down host cell replication and lyse tumour cells. Ad5 of species C is commonly used as a replication-defective or a replication-competent vector. READ MORE