Search for dissertations about: "Guo-Zhong Fei"

Found 1 swedish dissertation containing the words Guo-Zhong Fei.

  1. 1. Chronic hepatitis B : immunological, virological and clinical aspects in the natural course and during the combined prednisolone and interferon-alpha-2b therapy

    Author : Guo-Zhong Fei; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HBV; IgM and IgG anti-preS2; IgM anti-HBc; CD4 CD8 ratio; lymphocyte subpopulations; HBV DNA; ALT; chronic hepatitis; prednisolone; interferon-alpha;

    Abstract : The aims of this study were to characterize the IgM and IgG antibody responses to well-defined B-cell epitopes within the preS2 region of the HBV envelope proteins in sera from Chinese and Caucasian patients with chronic HBV infection in relation to viral load and liver disease activity. In addition, the effects of the combined prednisolone and interferon- alpha-2b therapy on these parameters, as well as on the peripheral lymphocyte subsets, were studied in Chinese patients with chronic hepatitis B. READ MORE