Advanced search

Found 4 swedish dissertations matching the above criteria.

2. 1. Leukocytes in Angiogenesis : Learning from Transplanted Pancreatic Islets

   Author : Gustaf Christoffersson; Mia Phillipson; Kristian Pietras; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; pancreatic islet transplantation; islets of Langerhans; diabetes mellitus; leukocytes; neutrophils; macrophages; pericytes; MMP-9; VEGF-A; Medical Science; Medicinsk vetenskap;

   Abstract : Angiogenesis, the growth of new blood vessels, is a complex process involving several cell types and molecular signals. Excessive vascular growth is a problem in tumors, and insufficient vascularization hampers the function of transplanted insulin-producing pancreatic islets. READ MORE

4. 2. Functional characterization of pro-angiogenic neutrophils

   Author : Jalal Lomei; Mia Phillipson; Gustaf Christoffersson; Johan Kreuger; Lars Olaf Cardell; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; leukocytes; neutrophils; pro-angiogenic neutrophils; islets transplantation; intravital microscopy; aortic ring assay; phagocytosis; ROS production; hypoxia; vascular permeability; neutrophil recruitment; Medical Cell Biology; Medicinsk cellbiologi;

   Abstract : The vascular system stretches throughout the body to provide oxygen, nutrition, and to remove waste products from cell metabolism. Angiogenesis, formation of new blood vessels by sprouting from pre-existing vessels, is one of the main mechanisms involved in blood vessel formation. READ MORE

5. 3. Integrative Approaches in Shotgun Proteomics : From sample preparation to multifaceted data analysis

   Author : Mariya Nezhyva; Erik T. Jansson; Per Andrén; Gustaf Christoffersson; Jesper Velgaard Olsen; Uppsala universitet; []
   Keywords : bottom-up proteomics; thermal proteome profiling; mass-spectrometry imaging; data analysis; melanocortin receptor; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Bottom-up proteomics mass-spectrometry gives an opportunity to shed light on var-ious biological aspects/characteristics such as protein composition, its modifications,interactions, and dynamics. Its applications span a wide range of biological sciencesaiming to eventually answer fundamental disease related questions or evaluate drugperformance and predict adverse effects. READ MORE

6. 4. Macrophages and neutrophils in tissue homeostasis and recovery from ischemic injury

   Author : Kristel Parv; Mia Phillipson; Gustaf Christoffersson; Per-Ola Carlsson; Stephen Jenkins; Uppsala universitet; []
   Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; macrophages; neutrophils; hindlimb ischemia; ischemic disease; mural cells; diabetes mellitus; postnatal β cell maturation.;

   Abstract : Neutrophils and macrophages have functions beyond protection against pathogens. The overall aim of the work presented in this thesis was to identify novel tasks for these innate immune cells in maintaining homeostasis. READ MORE