Search for dissertations about: "Guterstam"

Found 5 swedish dissertations containing the word Guterstam.

  1. 1. Multisensory mechanisms of body ownership and self-location

    Author : Arvid Guterstam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Having an accurate sense of the spatial boundaries of the body is a prerequisite for interacting with the environment and is thus essential for the survival of any organism with a central nervous system. Every second, our brain receives a staggering amount of information from the body across different sensory channels, each of which features a certain degree of noise. READ MORE

  2. 2. Imaging of the brain opioid system in amphetamine dependence

    Author : Joar Guterstam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Amphetamine dependence is a global health problem, often giving rise to severe medical and social complications in affected individuals. Unfortunately, there is still limited evidence for any specific treatment that would help amphetamine dependent patients to avoid relapse. READ MORE

  3. 3. Immune cell composition and cytokine expression in the pregnant and non-pregnant uterus

    Author : Ylva Crona Guterstam; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The success of implantation and further development of the embryo is heavily dependent on the endometrial immune cell composition and its ability to communicate with fetal semi-allogeneic trophoblast cells. Although our understanding of the immune cell population in the uterus has improved, its precise role in normal reproduction and reproductive disorders is still not fully resolved. READ MORE

  4. 4. Cell-penetrating peptides, novel synthetic nucleic acids, and regulation of gene function : Reconnaissance for designing functional conjugates

    Author : Peter Guterstam; Ülo Langel; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell-penetrating peptide; nucleic acids; alternative splicing; mismatch discrimination; Neurochemistry; Neurokemi;

    Abstract : Our genome operates by sending instructions, conveyed by mRNA, for the manufacture of proteins from chromosomal DNA in the nucleus of the cell to the protein synthesizing machinery in the cytoplasm. Alternative splicing is a natural process in which a single gene can encode multiple related proteins. READ MORE

  5. 5. Specificity of antisense oligonucleotide derivatives and cellular delivery by cell-penetrating peptides

    Author : Peter Guterstam; Ülo Langel; Matthew Wood; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell-penetrating peptide; splice-switching oligonucleotide; oligonucleotide derivative; Neurochemistry; Neurokemi; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Abstract : Atypical gene expression has a major influence on the disease profile of several severe human disorders. Oligonucleotide (ON) based therapeutics has opened an avenue for compensating deviant protein expression by acting on biologically important nucleic acids, mainly RNAs. READ MORE