Search for dissertations about: "Guy Dodson"

Found 1 swedish dissertation containing the words Guy Dodson.

2. 1. Tunnels and Grooves : Structure-Function Studies in Two Disparate Enzymes

   Author : Daniel Ericsson; Sherry Mowbray; Guy Dodson; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mycobacterium tuberculosis; ribonucleotide reductase; peptide inhibitors; fluorescence polarization; lipase; interfacial activation; hydrolase; X-ray structure; substrate specificity; Structural biology; Strukturbiologi;

   Abstract : This thesis describes structural and binding studies in enzymes from two different  organisms: ribonucleotide reductase from Mycobacterium tuberculosis (RNR) and lipase A from Candida antarctica (CalA).RNR is viable as a target for new drugs against the causative agent of tuberculosis. READ MORE