Search for dissertations about: "GvHD"
Showing result 11 - 15 of 69 swedish dissertations containing the word GvHD.
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11. Pathophysiological aspects of transplantation-related complications following busulphan/cyclophosphamide conditioning regimen in mouse model
Abstract : Hematopoietic stem cell transplantation (HSCT) is a curative treatment for several malignant and non-malignant disorders. However, transplantation related morbidity and mortality limit its use. The complications of the HSCT procedure can be caused by several factors including toxicity of the conditioning regimen and allogeneicity. READ MORE
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12. Methods and biomarkers for outcome prediction after allogeneic hematopoietic stem cell transplantation
Abstract : Allogeneic hematopoietic stem cell transplantation (HSCT) is a potent immunotherapeutic procedure but its usability is limited by a high risk of serious complications. A prerequisite for timely initiation of preventive measures is the availability of predictive methods. READ MORE
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13. Anti-tumour effect in solid tumours, tolerance and immune reconstition after allogeneic haematopoietic stem cell transplantation
Abstract : Both in haematological malignancies and in disseminated solid tumours, re-occurrence of the underlying disease is the main complication. Allogeneic haematopoietic stem cell transplantation (HSCT) increases the chance of cure compared to only chemotherapy in haematological malignancies, but adds the risk of immunological complications such as graft-versus-host disease (GVHD) and severe infections. READ MORE
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14. Allogeneic stem cell transplantation in children : identification and prevention of complications : adoptive transfer of EBV-immunity
Abstract : Allogeneic stem cell transplantation (SCT) can cure leukaemia, aplastic anaemia, and some inborn errors of metabolism and immunodeficiencies in children. As only 113 of patients who need SCT have an HLA-identical sibling, the use of alternative donors has increased, to over 50% of all paediatric SCTs at our centre. READ MORE
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15. From risk indices to reconstitution of immunity : studies of outcome-related factors in patients undergoing allogeneic hematopoietic stem cell transplantation
Abstract : Allogeneic hematopoietic stem cell transplantation (HSCT) is a potent immunotherapeutic procedure which has the possibility to cure otherwise lethal hematological diseases. Its usability in clinical practice is limited by tangible risks of detrimental transplantation-related complications. READ MORE