Search for dissertations about: "GvHD"

Showing result 21 - 25 of 69 swedish dissertations containing the word GvHD.

  1. 21. The panorama of infections in immunocompromised patients and in patients with an increased susceptibility to infections

    Author : Anna-Carin Norlin; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : The main objective of this thesis was to contribute to immunomodulatory interventions that are important for the clinical outcome in patients undergoing haematopoietic stem cell transplantation (HSCT) and in patients with antibody deficiency or increased susceptibility to infections. Graft-versus-host disease (GVHD), infections, and relapse of the underlying disease are the main complications after allogeneic haematopoietic stem cell transplantation. READ MORE

  2. 22. Outcome after allogeneic stem cell transplantation with special reference to non-malignant disorders, chimerism and graft cell composition

    Author : Petter Svenberg; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : The outcome for patients undergoing allogeneic stem cell transplantation (HSCT), a treatment for several severe malignant and non-malignant disorders with hematopoietic origin, is a balancing act between beneficiary effects and risk factors. Treatment success is still limited by excessive immune response, such as graft-versus-host–disease (GVHD) and graft failure (GF), or the lack thereof as in malignancy relapse or severe infections. READ MORE

  3. 23. Human cytomegalovirus (HCMV) : detection and elimination of infected blood cells in vitro, immune reactivity and complications following HCMV infection

    Author : Susanne Larsson; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Human cytomegalovirus (HCMV) belongs to the herpes virus family and establishes life-long persistence in a latent state following a primary infection. HCMV disease causes high morbidity in immunosuppressed individuals, such as bone marrow and organ transplant patients. READ MORE

  4. 24. Diversity and focus of CMV specific T-cell responses in patients post-HSCT and with solid tumor

    Author : Thomas Poiret; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Human Cytomegalovirus (CMV) is a beta-herpesvirus that commonly infects humans. Most symptoms in healthy individuals are very mild. The virus is never eliminated and remains in the individual life-long. Thus, CMV and the immune response stay in coexistence until the protective response remains. READ MORE

  5. 25. Acute gastrointestinal graft-versus-host disease in allogeneic hematopoietic stem cell transplanted children and adolescents : clinical aspects of histopathological evaluation and risk factors

    Author : Thomas Mårtensson; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Background: Acute graft-versus-host disease (aGVHD), following allogeneic hematopoietic stem cell transplantation (HSCT), is a potentially life-threating condition. Gastrointestinal involvement of aGVHD (GI-aGVHD) affects approximately every fourth transplanted child. The diagnosis of GI-aGVHD is primarily symptom-based. READ MORE