Search for dissertations about: "H. influenzae"

Showing result 1 - 5 of 42 swedish dissertations containing the words H. influenzae.

  1. 1. Structural diversity of the lipid A and core oligosaccharide moieties of the lipopolysaccharides from nontypeable and serotype f Haemophilus influenzae

    Author : Håkan H. Yildirim; Elke Schweda; Andrzej Gamian; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Haemophilus influenzae; LPS; biosynthesis; NMR; ESI-MS;

    Abstract : This thesis describes structural studies of the oligosaccharide and lipid A moieties of lipopolysaccharides (LPSs) isolated from disease-causing Haemophilus influenzae strains. The nontypeable strains were clinical isolates from the middle ear of children suffering from otitis media and the serotype f strains had been collected from three adults with respiratory tract infections. READ MORE

  2. 2. The structural diversity of lipopolysaccharides expressed by genetically defined clinical isolates of nontypeable Haemophilus influenzae

    Author : Martin Månsson; Elke K. H. Schweda; Jane Thomas-Oats; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nontypeable Haemophilus influenzae NTHi ; lipopolysaccharide LPS ; nuclear magnetic resonance NMR spectroscopy; electrospray ionization mass spectrometry ESIMS ; structural analysis.;

    Abstract : Nontypeable Haemophilus influenzae (NTHi) is an important cause of otitis media and respiratory tract infections. Its lipopolysaccharide (LPS) molecule, an outer membrane component, is a major virulence factor of NTHi. The LPS molecule may also be an efficient target for antibodies which might be protective against NTHi disease. READ MORE

  3. 3. Immunogenicity and protective potential of Protein D of Haemophilus influenzae against H. influenzae infection

    Author : Mustafa Akkoyunlu; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bactericidal assay; mucosal immunity; otitis media; vaccine; H. influenzae; protein D; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Both Haemophilus influenzae type b (Hib) and nontypeable H. influenzae (NTHi) are important human pathogens causing invasive and mucosal infections. Currently there are number of vaccines available against Hib infections. READ MORE

  4. 4. Invasive disease by Haemophilus influenzae in Sweden in the era of the H. influenzae type b vaccine

    Author : Fredrik Resman; Enheten för infektionssjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haemophilus influenzae; sepsis; epidemiology; antimicrobial resistance; bacterial adhesion;

    Abstract : What is the current status of Haemophilus influenzae as an agent of invasive infection in Sweden? H. influenzae type b (Hib) used to be a common cause of meningitis, epiglottitis and severe sepsis in young children. READ MORE

  5. 5. Haemophilus influenzae – typing, epidemiology and beta-lactam resistance

    Author : Viktor Månsson; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; benzylpenicillin; beta-lactam resistance; beta-lactams; BLNAR; capsule typing; clonal; Haemophiilus influenzae; Hib; MALDI-TOF MS; MLST; NTHi; serotyping; virulence; epidemiology;

    Abstract : Haemophilus influenzae is a common cause of respiratory tract infections such as acute otitis media (AOM), exacerbations of chronic obstructive pulmonary disease (COPD) and pneumonia. The species is subdivided into encapsulated and non-encapsulated strains, designated type a-f and nontypeable H. influenzae (NTHi), respectively. READ MORE