Search for dissertations about: "H19"

Showing result 21 - 24 of 24 swedish dissertations containing the word H19.

  2. 21. Genomic and epigenetic investigations of Silver-Russell syndrome and growth restriction

    Author : Sara Bruce; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : A combination of genes, their epigenetic regulation, and the environment control the phenotypes of an individual, such as how short or tall one grows. Epigenetics refers to chemical modifications of DNA and histones that regulate gene activity and genome stability, and can take the form of, for example, addition of a methyl group to DNA. READ MORE

  4. 22. Epigenetic regulation of higher order chromatin conformations and networks

    Author : Chengxi Shi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Higher order chromatin conformations result from the packaging of the genome into the physical confines of the cell nucleus. Structural hallmarks of the nucleus influence the spatio-temporal behavior of genome underlying the regulation of genomic functions. READ MORE

  5. 23. TARP Promoter-Based Prostate Cancer Gene Therapy : From Development to Application

    Author : Wing-Shing Cheng; Magnus Essand; Thomas H. Tötterman; Cecilia Lundberg; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Genetic engineering; TARP; PPT; TSTA; promoter; gene regulation; prostate specificity; hormone- independent; adenovirus; prostate cancer; gene therapy; conditionally replicating adenovirus; Genteknik; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Abstract : Prostate cancer is one leading cause of cancer-related death among men in Western countries. The standard therapies for localized prostate cancer include radical prostatectomy and radiation therapy. Such measures are relatively effective in the short term, but many patients ultimately relapse. READ MORE

  6. 24. Differential microRNA and metabolic expressions in neuroendocrine and cervical carcinomas

    Author : Patrick Scicluna; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : MicroRNAs (miRNAs) are important regulators of many biological processes involved in cancer development and progression. However, the functional roles of miRNAs in some cancer types are still poorly understood. READ MORE