Search for dissertations about: "HBeAg"

Showing result 11 - 15 of 16 swedish dissertations containing the word HBeAg.

  2. 11. Characterisation of the interaction between the Hepatitis B virus core antigen and B cells

    Author : Una Lazdina; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HBcAg; B cells; B cell antigen receptor; co-stimulatory molecules; cytokines; T helper cells; cytotoxic T cells;

    Abstract : The Hepatitis B virus (HBV) is a major cause of severe human liver disease globally. There are around 350 million persistent HBV carriers with a risk of development of liver disease including cirrhosis and hepatocellular carcinoma. READ MORE

  4. 12. Functional role of T-cell activation in viral hepatitis

    Author : Jessica Nyström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HBV; HCV; HBcAg; NS3 4A; HBsAg; T-cells;

    Abstract : Hepatitis B and C (HBV, HCV) constitute global health problems and there are approximately 350 million chronically HBV infected people around the world, most of them are found in East and South East Asia and Africa. Worldwide there are 170 million HCV infected individuals with the highest prevalence seen in Egypt. READ MORE

  5. 13. The hepatitis B virus – Insights into genetic variability, evolution and Bayesian phylogeographic inference

    Author : Mikael Ingman; Malmö Klinisk virologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatit B; evolutionsbiologi; fylogeni; Hepatitis B; evolutionary dynamics; Phylogeography;

    Abstract : In terms of genome size, the hepatitis B virus is the smallest virus known to infect humans and its compactness with multiple overlapping reading frames puts restraints on the emergence of mutations. In the papers included in this thesis we aimed to investigate genetic variation within the precore and core promoter region and to describe the origin, spread and diversification of HBV genotype A. READ MORE

  6. 14. Geographic and genetic diversity of hepatitis B

    Author : Erik Alestig; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis B virus; genotype; phylogeny; molecular epidemiology; sequence analysis; mutation;

    Abstract : Hepatitis B Virus (HBV) infection is a global health problem and may lead to chronic hepatitis, liver cirrhosis and hepatocellular cancer. The ability of HBV to adapt to the host environment by genetic variation has lead to the evolution of 8 established (A-H) and 2 putative genotypes (I-J), each corresponding to a rather well-defined geographical distribution. READ MORE

  7. 15. Development of vaccines and mouse models for chronic hepatitis C virus infection

    Author : Sepideh Levander; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chronic hepatitis C virus (HCV) infection is a major causative agent for severe liver disease and cancer worldwide. Globally, it is estimated that approximately 185 million people are infected with HCV and 130-170 million of these are chronic carriers of the virus (1, 2). READ MORE