Search for dissertations about: "HCC"

Showing result 6 - 10 of 67 swedish dissertations containing the word HCC.

  1. 6. In vivo studies of cell cycle regulating proteins in rats during liver regeneration and during promotion of liver carcinogenesis

    Author : Lena Ohlson; Inger Porsvh Hällström; Galina Selivanova; Bertha A. Brodin; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell cycle; cancer; HCC; p53; Rb; p107; G1-progression; G1 S transition;

    Abstract : There are more than one hundred different types of cancer in humans. However, the major platform for all types of cancer is automous and uncontrolled cell division and though most types of cancer are possible to treat and cure by surgery, chemical therapy or irradiation, more efficient and less toxic therapies are urgently needed. READ MORE

  2. 7. Some epidemiological aspects of liver cirrhosis and hepatocellular carcinoma in Sweden

    Author : Juan Vaz; Allmänmedicin och samhällsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver cirrhosis; Hepatocellular carcinoma; Epidemiology; Socioeconomic Status; Survival Analysis; Etiology; Sweden;

    Abstract : Background: Contemporary epidemiological studies examining incidence rates (IR) of cirrhosis and hepatocellular carcinoma (HCC) in Swedish populations are scarce. Cirrhosis and HCC are associated with a significant burden of health inequity and stigma. READ MORE

  3. 8. Harnessing T cell immunity for the prevention and treatment of liver cancer

    Author : Panagiota Maravelia; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hepatocellular carcinoma (HCC) accounts for more than 80% of all diagnosed cases of liver cancer which is a major cause of cancer related fatalities worldwide. With few improvements in the survival rates during the last decades, prevention of HCC is key in reducing its burden globally. READ MORE

  4. 9. Liver cirrhosis : epidemiology, prognosis, and cancer

    Author : Bonnie Bengtsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Liver cirrhosis is a major risk factor for hepatocellular carcinoma (HCC). Patients with liver cirrhosis also have a high risk to develop infections leading to deterioration of liver function and increased mortality. READ MORE

  5. 10. Tumor-stroma interactions in hepatocellular carcinoma

    Author : Nataša Pavlović; Femke Heindryckx; Jessica Maiers; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatocellular carcinoma; fibrosis; endoplasmic reticulum stress; unfolded protein response; platelets; P2Y12; Molekylär cellbiologi; Molecular Cellbiology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Abstract : Hepatocellular carcinoma (HCC), a highly deadly primary liver cancer with a rising global incidence and limited therapeutic options, is characterized by a vicious cross-talk between the tumor and its surrounding hepatic stroma. The stromal environment, consisting of hepatic stellate cells (HSC), endothelial cells, resident and infiltrating macrophages and other immune cells, platelets and extracellular matrix (ECM) components, actively contributes to creating an ideal niche for tumor proliferation and invasiveness. READ MORE