Search for dissertations about: "HDC"

Showing result 1 - 5 of 12 swedish dissertations containing the word HDC.

  1. 1. Characterization of Endocrine Cells and Tumours in the Stomach

    Author : Apostolos V. Tsolakis; Eva T. Janson; Mats Stridsberg; Guida M. Portela-Gomes; Ola Nilsson; Uppsala universitet; []
    Keywords : Oncology; ECL cells; ghrelin cells; gastric endocrine tumours; VMAT-2; ghrelin; obestatin; HDC; U-MeImAA; Onkologi;

    Abstract : Enterochromaffin-like (ECL) and ghrelin cells, in the human gastric mucosa and in gastric endocrine tumours (GETs), were subclassified with respect to immunohistochemical reaction vs. vesicular monoamine transporter 2 (VMAT-2), ghrelin/obestatin, and histidine decarboxylase (HDC). READ MORE

  2. 2. Effect of Cholecystokinin-B/Gastrin Receptor Antagonists on Rat Stomach ECL Cells

    Author : Xi-Qin Ding; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacognosy; Pharmacological sciences; vävnadskultur; histokemi; cytokemi; Histologi; tissue culture; histochemistry; gastrin; cholecystokinin CCK receptors; ECL cells; CCK-B gastrin receptor antagonists; histidine decarboxylase HDC ; histamine; pancreastatin; chromogranin A CGA ; gastric acid secretion.; cytochemistry; Histology; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : The histamine- and pancreastatin- containing ECL cells in the acid-producing mucosa of the rat stomach operate under the control of circulating gastrin. The present work examines how cholecystokinin (CCK)-B/gastrin receptors regulate the activity of the ECL cells. READ MORE

  3. 3. Molecular regulation of rat histidine decarboxylase

    Author : Christine Dartsch; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Physiology; omeprazole; antiserum; fetal rat liver; COS-7 cells; purification; bacterial expression; protein turnover; ECL cells; gastric mucosa; gastrin; histdine decarboxylase; histamine; Fysiologi; Proteins; enzymology; Proteiner; enzymologi;

    Abstract : Histamine is involved in a variety of physiological processes like gastric acid secretion, inflammation and neurotransmission. The production of histamine is catalysed by the enzyme histidine decarboxylase (HDC), which is a strongly regulated enzyme. READ MORE

  4. 4. Immunotherapy and immunosuppression in myeloid leukemia

    Author : Alexander Hallner; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Natural killer cells; acute myeloid leukemia; histamine dihydrochloride; immunotherapy; reactive oxygen species; chronic myelomonocytic leukemia; NK cell education; NKG2A; HLA; KIR;

    Abstract : Acute myeloid leukemia (AML) and chronic myelomonocytic leukemia (CMML) are potentially life-threatening blood cancers characterized by the expansion of malignant myeloid cells in bone marrow and other organs. This thesis aimed at contributing to the understanding of the role of natural killer (NK) cells in AML and CMML with focus on the potential impact of the immunosuppression exerted by reactive oxygen species (ROS) formed by the myeloid cell NOX2 enzyme. READ MORE

  5. 5. Studies of Autoantibodies in Systemic and Organ-Specific Autoimmune Disease

    Author : Filip Sköldberg; Olle Kämpe; Fredrik Rorsman; Lars Rönnblom; Eva Landgren; Marie Wahren-Herlenius; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; autoantibodies; autoimmune polyendocrine syndrome type 1; cysteine sulfinic acid decarboxylase; histidine decarboxylase; systemic lupus erythematosus; ahnak; CLLD4; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Molekylär medicin; Molecular Medicine;

    Abstract : Systemic lupus erythematosus (SLE) is the prototypic systemic autoimmune disease, whereas autoimmune polyendocrine syndrome type 1 (APS1) is a rare autosomal disorder characterized by combinations of organ-specific autoimmune manifestations including hypoparathyroidism and intestinal dysfunction, and may serve as a model for organ-specific autoimmunity. Autoantibodies directed against proteins expressed in the affected tissues are found in both diseases. READ MORE