Search for dissertations about: "HDL"

Showing result 6 - 10 of 12924 swedish dissertations containing the word HDL.

  2. 6. Immunotherapy with the anti-EpCAM monoclonal antibody and cytokines in patients with colorectal cancer : a clinical and experimental study

    Author : Maria Gustafsson Liljefors; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Colorectal carcinoma; monoclonal antibodies; GM-CSF; pharmacokinetics; prognosis; bone marrow micrometastases; cytokeratin-positive cells; Colorectal carcinoma;

    Abstract : The tumor-associated antigen EpCAM (epithelial cell-adhesion molecule) (C017-1A) is over expressed by various human carcinomas, including colorectal carcinoma (CRC). This antigen can be used as a target structure for specific immunotherapy with vaccines and monoclonal antibodies (MAb). READ MORE

  4. 7. The central role of the CD4 T-helper cell in HIV infection : analysis of cell mediated responses and CCR-5 genotypes in HIV-1 infected individuals

    Author : Ann-Charlotte Leandersson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human immunodeficiency virus (HIV) infection is characterized by progressive immunologic dysregulation. The main target of HIV is the CD4 cell resulting in malfunction of the immune system, with a decline in CD4 cells and subsequent development of the acquired immunodeficiency syndrome (AIDS). READ MORE

  5. 8. Primary HIV-1 infection : diagnostic, prognostic, and therapeutic aspects

    Author : Stefan Lindbäck; Karolinska Institutet; Karolinska Institutet; []
    Keywords : primary HIV- I infection; diagnosis; prognosis; HIV-RNA; antiretroviral treatment; primary HIV-1 infection; diagnosis; prognosis; HIV-RNA; antiretroviral treatment;

    Abstract : Primary HIV-1 infection (PHI) is usually defined as a mononucleosis-like illness associated with seroconversion to HIV. In earlier studies using 1st generation antibody tests, the duration of the 'window period' from infection to detection of specific HIV-antibodies, could be 2 to 3 months, or longer. READ MORE

  6. 9. Functional studies of the ubiquitin proteasome system using GFP based reporters

    Author : Kristina Lindsten; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Ubiquitin; proteasome; green fluorescent protein GFP ; degradation; inhibitor; Gly-Ala repeat; neurodegencration; poly-Gln aggregates.;

    Abstract : Ubiquitin-dependent proteasomal degradation is of paramount importance for cellular processes such as cell cycle progression, transcriptional regulation, apoptosis and disposal of misfolded and aberrant proteins. Moreover the ubiquitin-proteasome system is the main producer of peptides used by major histocompatibility complex class 1 for antigen presentation. READ MORE

  7. 10. Impact of candidate genes on obesity and type 2 diabetes

    Author : Ewa-Carin Långberg; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Obesity and type 2 diabetes (T2D) have strong genetic components. Identification of susceptibility genes in both diseases will give better knowledge of their pathomechanisms and future therapies. READ MORE