Search for dissertations about: "HELIX FORMATION"

Showing result 1 - 5 of 66 swedish dissertations containing the words HELIX FORMATION.

  1. 1. Polypeptide-Based Nanoscale Materials

    Author : Daniel Aili; Bo Liedberg; Karin Enander; Molly Stevens; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gold nanoparticle; polypeptide; helix-loop-helix; four-helix bundle; self-assembly; folding; Chemistry; Kemi;

    Abstract : Self-assembly has emerged as a promising technique for fabrication of novel hybrid materials and nanostructures. The work presented in this thesis has been focused on developing nanoscale materials based on synthetic de novo designed polypeptides. READ MORE

  2. 2. Calcium regulation and functions of basic Helix-Loop-Helix transcription factors

    Author : Juha Saarikettu; Thomas Grundström; Dan Holmberg; Mikael Sigvardsson; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; calcium; calmodulin; calretinin; transcription; bHLH; E-protein; E2-2; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The members of the ubiquitously expressed E-protein subfamily of basic Helix-Loop-Helix (bHLH) transcription factors, E12/E47, SEF2-1 and HEB, have important roles as regulators of gene expression in various differentiation processes, including lymphocyte development and myogenesis. In myogenesis, E-proteins are proposed to function as obligate heterodimer partners for members of the MyoD family of muscle-specific bHLH transcription factors. READ MORE

  3. 3. Molecular mechanisms in amyloid fibril formation

    Author : Waltteri Hosia; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis concerns investigations on molecular processes and interactions that lead to amyloid fibril formation. Pulmonary surfactant protein C (SP-C), and a synthetic analogue thereof, SP-C(Leu), have similar properties in terms of charge distribution, hydrophobicity and secondary structure, yet they differ in their aggregation propensities. READ MORE

  4. 4. Protein misfolding and amyloid formation : strategies for prevention

    Author : Charlotte Nerelius; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Most proteins need to adopt a three-dimensional structure in order to function properly. Misfolding, or inability of proteins to fold, is associated with a number of diseases. In a subset of these disorders, the misfolded protein or peptide selfassembles into stable, β-sheet rich structures known as amyloid fibrils. READ MORE

  5. 5. Investigations on Reducing Burr Formation in Metal Cutting

    Author : Vijay Sharan; Industriell Produktion; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Metal cutting is a very common operation in the manufacturing industry. Drilling and other hole-making operations perhaps account for 50% of all metal cutting, according to some investigations. All metal cutting including drilling always produces burrs, as a by-product. READ MORE