Search for dissertations about: "HEN1"

Found 2 swedish dissertations containing the word HEN1.

2. 1. Transcriptional regulation and effects on differentiation by LMO proteins and the basic helix-loop-helix factors TAL1 and HEN1

   Author : Anders Hansson; Institutionen för translationell medicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetik; cytogenetik; cytogenetics; Genetics; HEN1; differentiation; LMO; LIM proteins; TAL1; T-ALL; bHLH;

   Abstract : Acute lymphoblastic leukemia (ALL) is the most widespread type of cancer, as well as the most frequent leukemia in children. Malignant ALL cells originate from normal T lymphocytes or B cells that are blocked at immature stages of differentiation. READ MORE

4. 2. Transcriptional networks in neuroblastoma and breast cancer

   Author : Christina Manetopoulos; Institutionen för translationell medicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; basic helix-loop-helix; Neuroblastoma; Breast cancer;

   Abstract : Transcription factors of the basic Helix-loop-helix (bHLH) family of proteins are important regulators of cellular processes such as proliferation and differentiation. Many cancer diseases show a block in differentiation, and aberrant regulation of several bHLH factors have been implicated in the development of different malignancies. READ MORE