Search for dissertations about: "HETEROGENEITY"

Showing result 6 - 10 of 1275 swedish dissertations containing the word HETEROGENEITY.

  2. 6. Experimental studies on multidrug resistance in human leukaemia : role of cellular heterogeneity for daunorubicin kinetics

    Author : Eva Knaust; Curt Peterson; Anna Porwit-MacDonald; Astrid Gruber; Christer Paul; Linköpings universitet; []
    Keywords : Acute myeloid leukaemia; heterogeneity; multidrug resistance. transport kinetics flow cytometry; gene expression; mdr1; mrp; lrp; apoptosis. bcl-2; p53; MEDICINE; MEDICIN;

    Abstract : Cellular resistance to chemotherapy is a major cause of treatment failure in acute myeloid leukaemia (AML) and still the majority of the patients die from their disease. Drug resistance 1s multifactorial, the most studied mechanism being multidrug resistance (MDR), mediated by the P-glycoprotein (Pgp). READ MORE

  4. 7. Aspects of heterogeneity : effects of clear-cutting and post-harvest extraction of bioenergy on plants in boreal forests

    Author : Marcus Åström; Christer Nilsson; Katherine Frego; Umeå universitet; []
    Keywords : aspect; clear-cutting; disturbance; habitat quality; liverworts; logging residues; mosses; resilience; slash; slope; topography;

    Abstract : Abstract. The objectives of this thesis are to evaluate (1) the influence of slope aspect on boreal plant responses to clear-cutting and (2) the effects of post-harvest extraction of bioenergy (logging residues or slash) on plant composition, richness and performance in clear-cuts. READ MORE

  5. 8. Modeling flow and transport in fractured rock : role of heterogeneity, support scale and transport channeling

    Author : Magnus Oden; Uppsala universitet; []
    Keywords : fractured rock; modeling; heterogeneity; stochastic models; scale;

    Abstract : .... READ MORE

  6. 9. Language policy from below : Bilingual education and heterogeneity in post-apartheid South Africa

    Author : Peter Plüddemann; Christopher Stroud; Nancy Hornberger; Stockholms universitet; []
    Keywords : HUMANIORA; HUMANITIES; bilingual education; mother tongue; language policy from below; heterogeneity; multilingualism; language ideology; South Africa; tvåspråkighetsforskning; Bilingualism;

    Abstract : The present thesis on bilingual education, with its foci on linguistic heterogeneity and language policy 'from below', covers the first 15 years in the officially multilingual new South Africa. The post-apartheid era has seen South Africa's pro-multilingual Constitution and the language-in-education policy for schools being sidelined in favour of an English-oriented mindset. READ MORE

  7. 10. Computational Analysis of Tumour Heterogeneity

    Author : Stefanie Friedrich; Erik Sonnhammer; Martin Hemberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; tumour heterogeneity; human genome and gene expression analyses; pathway annotation; fusion transcript detection; copy number calling; and high-resolution data; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

    Abstract : Every tumour is unique and characterised by its genetic, epigenetic, phenotypic, and morphological signature. The diversity observed between and within tumours, and over time, is termed tumour heterogeneity. An increased heterogeneity within a tumour correlates with cancer progression, higher resistance rates, and poorer outcome. READ MORE