Search for dissertations about: "HIV ANTIBODIES IN BLOOD"

Showing result 1 - 5 of 36 swedish dissertations containing the words HIV ANTIBODIES IN BLOOD.

  2. 1. Effects of galectins and antibodies in HIV infection; Novel Assays

    Author : Enas Sheik-Khalil; Institutionen för laboratoriemedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; galectin-1; galectin-8; neutralizing antibodies; cell-cell fusion; Microscale anisotropy assay; virus binding assay; glycosylation; gp120; Automated plaque reduction assay; CellProfiler; NeutNet;

    Abstract : The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. READ MORE

  4. 2. Virus tropism and neutralization response in SIV infection

    Author : Anna Laurén; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Naturvetenskap; Natural science; Medicin människa och djur ; Medicine human and vertebrates ; HIV; SIV; mode of CCR5 use; CD4-independence; macrophage tropism; coreceptor use; neutralization; evolution; pathogenesis;

    Abstract : Simian immunodeficiency virus (SIV) infections in macaques are commonly used as models to study the pathogenesis of human immunodeficiency virus (HIV). Both SIV and HIV normally use the CD4 receptor and an additional coreceptor for cell entry. The most common coreceptors used by HIV are CCR5 and CXCR4. READ MORE

  5. 3. Functional properties of antibodies in resistance against HIV-1 infection

    Author : Claudia Devito; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : During the last years a few populations who remain uninfected despite repeated HIV-1 viral exposures have been described. Several mechanisms were suggested to be associated with this natural resistance including HIV-1-specific cell- mediated and humoral immune responses, as well as mutations affecting receptors for virus entry. READ MORE

  6. 4. HIV-1 infection in Tanzania : HIV antibody testing strategies and lymphocyte subset determinations

    Author : Willy Shileanga Kikoka Urassa; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HIV; antibody detection; alternative confirmatory strategy; lymphocyte subsets; Tanzania; Africa.;

    Abstract : The objectives of the studies that are reported in this thesis were to evaluate HIV antibody testing strategies and prognostic markers and to study inummological deterioration of HIV-1 infected individuals. Alternative testing strategies for confirmation of HIV seropositivity were evaluated using combinations of screening assays. READ MORE

  7. 5. Evaluation of HIV testing strategies and monitoring of immune responses in HIV-vaccinated individuals in Tanzania

    Author : Said Aboud; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis describes studies on the evaluation of human immunodeficiency virus (HIV) enzyme-linked immunosorbent assays (ELISAs) and simple rapid HIV assays for use in HIV testing strategies in resource-limited settings and studies of HIV vaccine-induced immune responses. Peripheral blood mononuclear cell (PBMC) preparation techniques were also studied in preparation for use in the HIV vaccine trials. READ MORE