Search for dissertations about: "HIV-Tat"

Found 5 swedish dissertations containing the word HIV-Tat.

2. 1. REGULATED UPTAKE OF BIOPOLYMERS Role of cell surface proteoglycans Implications for drug and gene delivery

   Author : Staffan Sandgren; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Cytology; oncology; proliferation; differentiation; Medicine human and vertebrates ; growth factor; cancer; drug delivery; gene therapy; LL-37; HIV-Tat; cell penetrating peptides; polyamines; heparan sulfate; onkologi; Cytologi; cancerology; internalization; proteoglycans;

   Abstract : Cells continuously export, import, and recycle molecules over the plasma membrane. Internalization, i.e. cellular import of extracellular material, is a fundamental process, which provides cells with nutrients and enables the immune cells of higher organisms to remove debris, sample their surroundings for antigens and to fight microbes. READ MORE

4. 2. AIDS and endemic Kaposi's sarcoma development : comparison by histopathology, virology (HHV8/KSHV) and cytogenetics

   Author : Pawan Pyakurel; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Kaposi’s sarcoma (KS) is a highly and abnormally vascularized tumor-like lesion with spindle cells (SC) affecting the skin, lymphnodes and viscera which is found in four different clinico-epidemiological forms as Classic KS (CKS), Iatrogenic KS (IKS), Endemic KS (EKS) and AIDS-associated KS (AKS). All KS forms develop from early stages of patch/plaque to late, nodular tumors and are associated with Kaposi's sarcomaassociated herpesvirus or human herpesvirus-8 (KSHV/ HHV-8). READ MORE

5. 3. Effects of influenza A virus infections and interferon-gamma on synapse formation and function in hippocampal neurons in culture

   Author : Johan Brask; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Influenza A virus; hippocampal neurons; interferon-gamma; electrophysiology; synapses.;

   Abstract : The central nervous system (CNS) can be the target for several infections that include those with RNA viruses. The parenchyma of the CNS is considered an immuneprivileged site since it is protected behind the blood-brain barrier, expresses no or only low levels of major histocompatibility complex (MHC) molecules and contains a paucity of antigenpresenting cells that prime an immune response. READ MORE

6. 4. HHV-8/KSHV association with tumor cells during development of Kaposi sarcoma

   Author : Fatemeh Pak; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Kaposi's sarcoma (KS) is a highly and abnormally vascularized tumor-like lesion which usually presents as a cutaneous disease and progresses to extracutaneous, systemic spread usually in the gastrointestinal (GI) tract, lungs, oral cavity and lymph nodes. It is the most common neoplasm of AIDS patient and included in the staging of HIV disease progression. READ MORE

7. 5. Development of AIDS associated and endemic Kaposi sarcoma : HHV-8/KSHV viral load in cutaneous and oral tumor cells

   Author : Fatemeh Pak; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Oral Kaposi s sarcoma . HHV-8 . immunohistochemistry; PCR ; lymphatic ascular endothelium;

   Abstract : Kaposi's sarcoma (KS) is a highly and abnormally vascularized tumor-like lesion which usually presents as a cutaneous lesion and eventually progresses to systemic disease usually in the gastrointestinal (G1) tract, lungs, oral cavity and lymph nodes. Whether KS represents a predominantly monoclonal neoplastic cell proliferation or a hyperplastic, reactive polyclonal process is still controversial. READ MORE