Search for dissertations about: "HLA, kidney"

Showing result 1 - 5 of 7 swedish dissertations containing the words HLA, kidney.

  2. 1. HLA and disease : studies in patients with arthritis, diabetes, inflammatory bowel diseases, kidney stone disease and myasthenia gravis

    Author : Jan Säfwenberg; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 2. The clinical importance of non-HLA specific antibodies in kidney transplantation

    Author : Almahri Ayeda; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transplantation; non-HLA antibody;

    Abstract : The clinical significance of human leukocyte antigen (HLA) antibodies (Abs) for hyperacute, acute and chronic antibody-mediated rejection (AMR) of kidney allografts has been clearly demonstrated. AMR occurs in the absence of donor-reactive HLA Abs. READ MORE

  5. 3. Molecular mechanisms behind the liver-induced acceptance of renal grafts in highly sensitized patients

    Author : Madeleine Ingelsten; Göteborgs universitet; []
    Keywords : kidney transplantation; liver tolerance; HLA antibodies; dendritic cells; indoleamine 2; 3-dioxygenase; IL-10; natural killer cells;

    Abstract : Preformed antibodies directed at donor HLA are considered an absolute contraindication for kidney transplantation, because of the high risk of rejection. Thus, patients with high levels of HLA antibodies have little chance of receiving a kidney transplant. READ MORE

  6. 4. Genetics of Diabetes Subtypes. Characterization of novel cluster-based diabetes subtypes

    Author : Dina Mansour Aly; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Precision medicine; Diabetes Subclassification; genome-wide association studies; GWAS; genetic risk scores; GRS; chronic kidney disease; CKD; diabetic kidney disease; DKD; Estimated glomerular filtration rate; eGFR; ANDIS; diabetes; diabetics;

    Abstract : BACKGROUND: Type 2 diabetes (T2D) has been reproducibly clustered into five subtypes based on six-clinical variables; age at diabetes onset, body mass index (BMI), Glutamic acid decarboxylase autoantibodies (GADA), glycated hemoglobin (HbA1c) and insulin secretion and resistance estimated as HOMA2B and HOMA2IR derived from fasting glucose and Cpeptide. These subtypes have different disease progression and risk of complications. READ MORE

  7. 5. Utilization and allocation of organs for transplantation - medical and ethical aspects

    Author : Marie Omnell-Persson; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; estetik; metafysik; kunskapsteori; ideologi; Immunology; serology; transplantation; Immunologi; serologi; ideology; epistemology; aesthetics; metaphysics; Systematic philosophy; ethics; utilization; organ donation; kidney transplantation; Allocation; attitudes; Praktisk filosofi;

    Abstract : Great efforts have been made to find solutions to the shortage of organs, such as extending the donor pool by accepting so-called marginal donors and development of transplantation of organs from animals (xenotransplantation, xt). Due to the scarcity of organs, there is a long tradition of prioritizing among patients on the waiting list for transplantation. READ MORE