Search for dissertations about: "HLA DR"

Showing result 1 - 5 of 87 swedish dissertations containing the words HLA DR.

  1. 1. Autoantibodies related to type 1 diabetes in children

    Author : Camilla Skoglund; Johnny Ludvigsson; Rosaura Casas; Outi Vaarala; William Hagopian; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Type 1 diabetes is an autoimmune disease resulting from destruction of the insulin producing beta cells in the pancreas. The patients need life-long heavy treatment and still complications, both acute and later in life, are common. The incidence of type 1 diabetes has increased rapidly during the last decades, especially among young children. READ MORE

  2. 2. Fault-tolerance in HLA-based distributed simulations

    Author : Martin Eklöf; Rassul Ayani; Gary Tan; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HLA; fault-tolerance; distributed simulations; federate; federation; Computer engineering; Datorteknik;

    Abstract : Successful integration of simulations within the Network-Based Defence (NBD), specifically use of simulations within Command and Control (C2) environments, enforces a number of requirements. Simulations must be reliable and be able to respond in a timely manner. Otherwise the commander will have no confidence in using simulation as a tool. READ MORE

  3. 3. Human leukocyte antigen in sickness and in health : Ankylosing spondylitis and HLA in Sweden

    Author : Jessika Nordin; Kerstin Lindblad-Toh; Jennifer Meadows; Matthew Webster; Alison Meynert; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Disease genetics; Ankylosing spondylitis; HLA typing; Imputation; Inference; Sex-stratified; HLA-B*27 independent; Association tests; Functional validation; Bioinformatics; Bioinformatik; Molekylär genetik; Molecular Genetics;

    Abstract : The human leukocyte antigen (HLA) plays a major role in keeping us healthy, but some of the HLA alleles can contribute to disease susceptibility. One example is HLA-B*27, which confers increased susceptibility of ankylosing spondylitis and represents one of the strongest genetic associations found in any common human disease. READ MORE

  4. 4. Multiplex HLA-DR-DQ genotyping : for genetic epidemiology and clinical risk assessment

    Author : Ewa Lavant; Malmö högskola; []
    Keywords : HLA-DRB1; HLA-DQB1; HLA-DQA1; PCR-SSP; type 1 diabetes; celiac disease; autoimmune disease; capillary gel electrophoresis; genotyping;

    Abstract : The human leukocyte antigens (HLA) are highly polymorphic cell surface proteins encoded in the major histocompatibility complex (MHC) region on chromosome 6. The HLA system has been well known as transplantation antigens but the primary biological role of the HLA molecules is regulation of immune response by presenting peptide fragments to T-lymphocytes. READ MORE

  5. 5. HLA-DR transplantation antigens : tissue distribution and structure

    Author : Klas Wiman; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE