Search for dissertations about: "HLA antibodies"

Showing result 1 - 5 of 117 swedish dissertations containing the words HLA antibodies.

  2. 1. Multiplex HLA-DR-DQ genotyping : for genetic epidemiology and clinical risk assessment

    Author : Ewa Lavant; Malmö högskola; []
    Keywords : HLA-DRB1; HLA-DQB1; HLA-DQA1; PCR-SSP; type 1 diabetes; celiac disease; autoimmune disease; capillary gel electrophoresis; genotyping;

    Abstract : The human leukocyte antigens (HLA) are highly polymorphic cell surface proteins encoded in the major histocompatibility complex (MHC) region on chromosome 6. The HLA system has been well known as transplantation antigens but the primary biological role of the HLA molecules is regulation of immune response by presenting peptide fragments to T-lymphocytes. READ MORE

  4. 2. Serologic Markers in Screening for Coeliac Disease, Clinical significance and immunogenetic basis

    Author : Klas Sjöberg; Gastroenterologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastro-enterology; transglutaminase; specificity; sensitivity; prevalence; HLA; liver disease; endomysial antibodies; gliadin antibodies; diabetes; Autoimmune disease; coeliac disease; Gastroenterologi;

    Abstract : The prevalence of coeliac disease (CD) was initially estimated to 1/1537. Based on serial analysis [GA and endomysial antibodies (EMA)], the prevalence was 6/1970 (0.30%). In autoimmune chronic hepatitis 5. READ MORE

  5. 3. Anti-D antibodies : In vitro tests to predict the severity of hemolytic disease of the newborn

    Author : Jan-Olof Hildén; Lennart Rydberg; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The ability of different in vitro tests to predict the severity of hemolytic disease of the newborn (HDN) has been studied. When properly performed the traditional indirect antiglobulin titers (IAT) on maternal serum can be used to identify a low !iter group ~32 in which the fetus will not suffer from severe hemolytic disease and a high titer group ~1000 where all newboms will be affected. READ MORE

  6. 4. The clinical importance of non-HLA specific antibodies in kidney transplantation

    Author : Almahri Ayeda; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transplantation; non-HLA antibody;

    Abstract : The clinical significance of human leukocyte antigen (HLA) antibodies (Abs) for hyperacute, acute and chronic antibody-mediated rejection (AMR) of kidney allografts has been clearly demonstrated. AMR occurs in the absence of donor-reactive HLA Abs. READ MORE

  7. 5. HLA genetics in multiple sclerosis

    Author : Jenny Link; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Multiple sclerosis (MS) is a chronic disease in which both genetic and environmental risk factors contribute to disease susceptibility. MS patients suffer from inflammatory lesions in the central nervous system which results in demyelination of nerve cells, reduced neuronal activity and finally neurodegeneration. READ MORE