Search for dissertations about: "HMGCR"
Showing result 1 - 5 of 6 swedish dissertations containing the word HMGCR.
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1. Statins, HMGCR and Breast Cancer
Abstract : .... READ MORE
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2. The role of HMG-coenzyme A reductase (HMGCR) and statin medication in the Central Nervous System : Cognitive Functions, Metabolism, Feeding and Sleep Behaviour
Abstract : Millions of people are currently on statin medications (HMGCR inhibitors) to prevent cardiovascular diseases. Despite considerable central nervous system expression, little is known about HMGCR function in the brain. READ MORE
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3. Body constitution, statin use, and tumor characteristics. Implications for prognosis
Abstract : Breast cancer is an important cause of disease-burden and death in women. To prevent over- and undertreatment of breast cancer patients, new prognostic and predictive factors are needed. READ MORE
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4. Adverse drug effects on glucose and lipid metabolism: is human adipose tissue of importance?
Abstract : Many pharmacological agents that are widely prescribed in clinical practice have adverse metabolic effects, such as hyperglycaemia, insulin resistance, and diabetes. Among such drugs are antipsychotics, prescribed for treatment of schizophrenia; statins, which inhibit cholesterol synthesis and prevent cardiovascular events; finally, potent anti-inflammatory agents, glucocorticoids. READ MORE
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5. Targeting the role of statins in breast cancer – through translationally edged clinical trials
Abstract : AbstractBreast cancer incidence is increasing, and despite major progress in the treatment, breast cancer is still the leading cause of death from cancer among women. Thus, there is a constant need for new treatment options. READ MORE