Search for dissertations about: "HOMOLOG"

Showing result 1 - 5 of 122 swedish dissertations containing the word HOMOLOG.

2. 1. TERMINAL FLOWER2, the Arabidopsis HETEROCHROMATIN PROTEIN1 Homolog, and its Involvement in Plant Development

   Author : Katarina Landberg; Annika Sundås Larsson; Peter Engström; Ove Nilsson; Uppsala universitet; []
   Keywords : Biology; Arabidopsis; HETEROCHROMATIN PROTEIN1; flowering; meristem; auxin; Biologi;

   Abstract : This thesis describes the characterization of the Arabidopsis thaliana mutant terminal flower2 (tfl2), the cloning of the corresponding gene, and the analysis of TFL2 function in plant development. The tfl2 mutant is pleiotropic, exhibiting early floral induction in both long and short day conditions, a terminating inflorescence and dwarfing. READ MORE

4. 2. α-Secretase processing of the Alzheimer amyloid-β precursor protein and its homolog APLP2

   Author : Kristin Jacobsen; Kerstin Iverfeldt; Olav Andersen; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; APP; APLP2; ADAM10; TACE; Alzheimer s Disease; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Abstract : The amyloid-β precursor protein (APP) has been widely studied due to its role in Alzheimer´s disease (AD). When APP is sequentially cleaved by β- and γ-secretase, amyloid-β (Aβ) is formed. Aβ is prone to aggregate and is toxic to neurons. READ MORE

5. 3. Genetic Sex Differences in Early Human Neuronal Development : An Investigation in Embryo Tissue and Embryonic Stem Cells

   Author : Philipp Pottmeier; Elena Jazin; Armin Raznahan; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sex chromosome; gametolog; x y homolog; male; female; sex differences; sex bias; embryonic stem cells; neurodevelopment; neuronal differentiation; neural stem cells; genetics; neurodevelopmental disorders; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi; Neuroscience; Neurovetenskap; Medicinsk genetik; Medical Genetics;

   Abstract : Sex differences in the human body affect many different organs and tissues, some of them have an effect on the human brain and its development. In the developing nervous system, sex differences can bias the number or functionality of neurons, glial cells or synapses. As a result, neural networks might develop with a sex-specific bias. READ MORE

6. 4. Novel RelA-SpoT Homolog toxin-antitoxin systems that inhibit bacterial growth through production of toxic alarmone ppApp

   Author : Steffi Jimmy; Vasili Hauryliuk; Vicky Shingler; Michael T. Laub; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; p ppGpp; ppApp; toxin; antitoxin; alarmone; antibacterials; molekylärbiologi; Molecular Biology; Biochemistry; biokemi;

   Abstract : The stress alarmone nucleotides guanosine pentaphosphate (pppGpp) and tetraphosphate (ppGpp), collectively known as (p)ppGpp, are the molecular mediators of the bacterial stringent response — a bacterial stress response implicated in virulence, antibiotic tolerance and biofilm formation. At high concentrations, (p)ppGpp halts bacterial growth, inhibits protein synthesis and rewires transcription and metabolism. READ MORE

7. 5. From QTLs to Genes: Flowering Time Variation and CONSTANS-LIKE Genes in the Black Mustard (Brassica nigra)

   Author : Marita Kruskopf Österberg; Martin Lascoux; Ulf Lagercrantz; Thomas Bataillon; Uppsala universitet; []
   Keywords : Molecular genetics; Flowering time; Brassica nigra; CONSTANS; CONSTANS-LIKE 1; Genetik;

   Abstract : The transition to flowering is a major developmental switch in angiosperms, the timing of which is expected to be important for fitness. In this thesis the focus has been on identification of genes affecting natural variation in flowering time in Brassica nigra. The background for this thesis is an earlier QTL-mapping study in B. nigra. READ MORE