Advanced search

Showing result 1 - 5 of 37 swedish dissertations matching the above criteria.

2. 1. An Epidemiological Study of Exhaustion in the Context of Chronic stress. Concept, Cortisol, Causes and Consequences

   Author : Sara Lindeberg; Socialmedicin och global hälsa; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic stress; cortisol; depression; exhaustion; gender; HPA activity; psychosocial;

   Abstract : The interest in exhaustion has increased rapidly during the last few decades in many developed countries. In Sweden, prevalence of exhaustion increased by 50 percent on average between 1989 and 2005, and recent data reveals that exhaustion still remains at this higher level. Scientifically, exhaustion is not clearly defined. READ MORE

4. 2. Personality and the HPA-axis in Association with Postpartum Depression

   Author : Stavros I Iliadis; Alkistis Skalkidou; Inger Sundström Poromaa; Erika Comasco; Sara Sylvén; Lil Träskman Bendz; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Corticotropin-releasing hormone; cortisol; HPA-axis; HSD11B1; hydroxysteroid 11-beta dehydrogenase 1; neuroticism; peripartum depression; personality; postpartum depression; rs12565406; stress; Obstetrik och gynekologi; Obstetrics and Gynaecology; Psychiatry; Psykiatri;

   Abstract : Postpartum depression is a psychiatric disorder affecting a substantial proportion of newly delivered women, and remains a significant cause of childbirth-related morbidity. The aim of the present thesis was to examine psychological, endocrine and genetic aspects of postpartum depression in a large, population-based sample of women in Uppsala, Sweden. READ MORE

5. 3. Studies on the deposition, bioavailability and systemic activity of glucocorticoids in man

   Author : Lars Thorsson; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacological sciences; systemic activity; glucocorticosteroids; lung deposition; systemic availability; inhalation; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

   Abstract : The local deposition, pharmacokinetics, and systemic activity of inhaled and intranasal glucocorticosteroids in different formulations and devices(ICSs) has been investigated. After nasal administration of the ICS budesonide (Bud), the systemic availability (F) was found to be significantly higher from an aqueous pump spray and from the powder inhaler Turbuhaler, than from a pressurized metered dose inhaler (pMDI), and the uptake process was slower and less complete with the pMDI formulation. READ MORE

6. 4. Examining Female Resilience to Early Environmental Influences : Short- and long-term consequences on behaviour, HPA axis activity and alcohol intake after prolonged maternal separation

   Author : Stina Lundberg; Erika Roman; Ingrid Nylander; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescence; Adulthood; Corticosterone; Early-life stress; Handling; Maternal deprivation; Multivariate concentric square field; MCSF; Sex differences; Social play behavior; Stress reactivity; Supplier differences; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Early-life experiences are an important factor influencing further development of the individual. Adverse experiences early in life, such as various kinds of abuse or neglect, are types of early-life stress that can adversely affect an individuals health, as well as contribute to the development of an array of disorders later in life. READ MORE

7. 5. Hypocortisolism in recurrent affective disorders

   Author : Martin Maripuu; Karl-Fredrik Norrback; Rolf Adolfsson; Mikael Wikgren; Marie Åsberg; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affective disorders; Bipolar disorder; Cortisol; Depression; HPA-axis; Hypercortisolism; Hypocortisolism; Lithium; Metabolic syndrome; Obesity; Quality of life; Recurrent depression; Stress; Telomeres;

   Abstract : Bipolar disorders and recurrent depressions are two common psychiatric disorders with a life time prevalence of approximately 1% and 8%, respectively. Despite treatment these patients suffer from affective symptoms up to 50% of the time, resulting in lower well-being. READ MORE