Search for dissertations about: "HPR-project"

Found 3 swedish dissertations containing the word HPR-project.

2. 1. Databases for antibody-based proteomics

   Author : Erik Björling; Mathias Uhlén; Alvis Brazma; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; proteomics; antibodies; database; biomarker; website; Bioengineering; Bioteknik;

   Abstract : Humans are believed to have ~20,500 protein-coding genes andmuch effort has over the last years been put into the characterizationand localization of the encoded proteins in order to understand theirfunctions. One such effort is the Human Proteome Resource (HPR)project, started in Sweden 2003 with the aim to generate specificantibodies to each human protein and to use those antibodies toanalyze the human proteome by screening human tissues and cells. READ MORE

4. 2. Selection of antigens for antibody-based proteomics

   Author : Lisa Berglund; Mathias Uhlén; Sören Brunak; KTH; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; epitope; antigen; antibody; affinity; protein; proteome; proteomics; bioinformatics; prediction; primer design; sequence similarity; Bioengineering; Bioteknik;

   Abstract : The human genome is predicted to contain ~20,500 protein-coding genes. The encoded proteins are the key players in the body, but the functions and localizations of most proteins are still unknown. READ MORE

5. 3. Affinity based proteomics research tools

   Author : Cecilia Eriksson; Sophia Hober; Michael Taussig; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Immunology; Immunologi; Molecular biology; Molekylärbiologi;

   Abstract : Listen to the mantra; the mapping of the genome was finished in 2001, and the sequel research challenge is the thorough survey of the corresponding human proteome. This was stated almost a decade ago, it has been repeated over and over, and is still most certainly a hard nut to crack. READ MORE