Search for dissertations about: "HPV-16"
Showing result 1 - 5 of 59 swedish dissertations containing the word HPV-16.
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1. Regulation of Human Papillomavirus Type 16 Late L1 mRNA Splicing
Abstract : Human papillomaviruses (HPVs) cause almost half of the human cancers that are attributable to viruses. HPV type 16 is the most carcinogenic type among the HPVs and is detected in 50% of all cervical cancers. HPV-16 infects epithelial cells and HPV-16 gene expression is tightly linked to the differentiation stage of the infected cells. READ MORE
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2. Regulation of RNA Processing in Human Papillomavirus Type 16
Abstract : Human papillomavirus type 16 (HPV-16) is the major cause of cervical cancer. HPV-16 gene expression is tightly linked to the differentiation programme of the infected epithelium. Expression of the late genes, L1 and L2, encoding the capsid proteins, is delayed until the more terminally differentiated cells. READ MORE
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3. Posttranscriptional Regulation of Human Papillomavirus Type 16 Late mRNAs
Abstract : The lifecycle of the human papillomavirus (HPV) is strictly linked to the programmed differentiation of the host cell it infects. Production of late proteins, which are used for the production of the major and minor capsid proteins, is only seen upon terminal differentiation of the epithelium. READ MORE
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4. The Role of Polyadenylation in Human Papillomavirus Type 16 Late Gene Expression
Abstract : High-risk type human papillomaviruses (HPVs) are associated with cancer. HPVs are strictly epitheliotropic and infect basal cell layers, establishing a life cycle strongly linked to the differentiation stage of the infected cells. The viral capsid late genes, L2 and L1, are only expressed in terminally differentiated epithelium. READ MORE
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5. Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element
Abstract : Human Papillomaviruses (HPVs) infect the epithelial tissues in humans and infection with certain high-risk types is associated with cancer. The expressionof the HPV late capsid genes is dependent on cell differentiation. This may be one reason for the lack of HPV replication in vitro. READ MORE