Search for dissertations about: "HPV-negative"

Showing result 1 - 5 of 30 swedish dissertations containing the word HPV-negative.

  1. 1. Human papillomavirus and cellular biomarkers in cervical cancer

    Author : Malin Kaliff; Gabriella Lillsunde-Larsson; Mats G. Karlsson; Tina Dalianis; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cervical cancer; HPV; screening; triage; prognosis; genotype distribution; multiple HPV; HPV-negative; viral load; methylation;

    Abstract : Cervical cancer (CC) is caused by a persistent infection of certain types of the human papillomavirus (HPV). Even though great progress has been made in strategies for prevention, and treatment of CC, there is still a need for improved methods in screening and management of women diagnosed with CC. READ MORE

  2. 2. Cervical carcinoma in Kampala, Uganda, and the relationship with human immunodeficiency virus and human papillomavirus infections

    Author : Michael Odida; Karolinska Institutet; Karolinska Institutet; []
    Keywords : HPV; Human Papillomaviruses; women; HIV; Uganda; invasive cervical cancer;

    Abstract : Introduction: Cervical carcinoma is the commonest tumour in Ugandan women. However, very little is known in the Ugandan population about HPV types associated with invasive cervical cancer, the relative risk of cervical cancer associated with different HPV types, and whether the risk of cervical cancer associated with HPV infection is modified by HIV infection. READ MORE

  3. 3. Studies on the presence and influence of human papillomavirus (HPV) in head and neck tumors

    Author : Liselotte Dahlgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Head and neck cancer; tonsillar cancer; tongue cancer; human papillomavirus; viral load; survival; comparative genomic hybridization; respiratory papillomatosis; Interferon-alpha;

    Abstract : The aim of this thesis was to confirm the presence of human papillomavirus (HPV) in tonsillar cancer and the previous finding that presence of HPV in tonsillar cancer is prognostic favorable for patient survival. Furthermore, the physical state and viral load of HPV in tonsillar cancer, and the influence of HPV on chromosomal patterns and on the clinical outcome for tonsillar cancer patients were examined. READ MORE

  4. 4. Novel functions of SMG-1 in carcinogenesis

    Author : Evgenia Gubanova; Thomas Helleday; Andrei Gudkov; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molekylärgenetik; Molecular Genetics;

    Abstract : Damage to DNA can cause mutations leading to cancer, and the DNA damage response (DDR), leading to transient cell-cycle arrest, DNA repair, senescence and apoptosis, plays a role in preventing tumor formation. At the same time, agents that damage DNA are used as anticancer therapy. READ MORE

  5. 5. Studies on the influence of human papillomaviruses (HPV) and other biomarkers on the prevalence of oropharyngeal cancer and clinical outcome

    Author : Anders Näsman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Oropharyngeal squamous cell carcinoma (OSCC), where tonsillar (TSCC) and base of tongue squamous cell carcinoma (BOTSCC) dominate, is increasing and is now the most common head and neck squamous cell carcinoma (HNSCC) in Sweden. Smoking and alcohol are risk factors for HNSCC, but in 2007, human papillomavirus (HPV) infection was also recognized as a risk factor for OSCC. READ MORE