Search for dissertations about: "HR-MAS NMR"

Found 4 swedish dissertations containing the words HR-MAS NMR.

  2. 1. Glucotoxicity in Insulin-Producing β-Cells

    Author : Hanna K Nyblom; Peter Bergsten; Michael Welsh; Miriam Cnop; Uppsala universitet; []
    Keywords : Cell biology; type 2 diabetes; SELDI-TOF MS; glucotoxicity; proteomics; insulin secretion; mitochondria; lipids; INS-1E cells; GC-MS; HR-MAS NMR; metabolomics; human islet; AMPK; AICAR; ER stress; apoptosis; Cellbiologi;

    Abstract : Background and aims: Type 2 diabetes mellitus is connected with elevated glucose levels, which cause impaired glucose-stimulated insulin secretion (GSIS) and degeneration of β-cells. Mechanisms for such glucotoxic effects were explored in the present study.Materials and methods: INS-1E cells were cultured for 5 days in 5. READ MORE

  4. 2. Study of retention mechanisms in Hydrophilic Interaction Chromatography by Nuclear Magnetic Resonance Spectroscopy

    Author : Adel Shamshir; Knut Irgum; Tobias Jonsson; Ngoc Phuoc Dinh; Torgny Fornstedt; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HILIC; hydrophilic interaction chromatography; adsorption; STD-NMR; saturation transfer difference; retention mechanism; NMRD; solid state-NMR; Analytical Chemistry; analytisk kemi;

    Abstract : This thesis deals with investigations of the retention mechanisms in hydrophilic interaction liquid chromatography (HILIC) using nuclear magnetic resonance spectroscopy. The aims are to understand how the different types of stationary phases can influence the retention of various solutes and the adsorption abilities of solvent on stationary phases. READ MORE

  5. 3. Carbohydrate and metabonomic studies by NMR spectroscopy

    Author : Gustav Nestor; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : NMR spectroscopy can be used to investigate organic and biomolecular structures, both as pure compounds and in complex mixtures. In this thesis NMR spectroscopy was used for carbohydrate and metabonomic studies. READ MORE

  6. 4. Spectroscopic data and multivariate analysis : tools to study genetic perturbations in poplar trees

    Author : Susanne Wiklund; Ulf Edlund; Olav Kvalheim; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NMR spectroscopy; Metabolomics; Degree of methylation; S-plot; SUS-plot; Metabonomics; Poplar; MLR; PLS; OPLS; PCA; Pectin; Wood; Organic chemistry; Organisk kemi;

    Abstract : In our society in the 21st century one of the greatest challenges is to provide raw materials to the industry in a sustainable way. This requires increased use of renewable raw materials such as wood. Wood is widely used in pulp, paper and textile industries and ongoing research efforts aim to extend the use of wood in e.g. READ MORE