Search for dissertations about: "HSV-tk"
Found 3 swedish dissertations containing the word HSV-tk.
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1. Two novel combination therapies of glioblastoma multiforme from a Cx43 perspective : studies of in vitro models
Abstract : The group of patients suffering from the malignant brain tumour glioblastoma multiforme (GBM) have a median survival of only about one year. Thus, new treatment strategies are urgently needed. Gap junctions are intercellular channels, permitting intercellular transfer of water soluble substances. READ MORE
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2. Neural stem cell-mediated enhanced gene therapy of malignant gliomas using a novel plant thymidine kinase
Abstract : Malignant gliomas are the most common brain tumors in adults. Approximately, 190,000 new patients are diagnosed with malignant gliomas worldwide every year. Unfortunately, the prognosis of malignant gliomas still remains very poor, despite advances in management. READ MORE
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3. Vector development for suicide gene therapy
Abstract : Gene therapy is used to treat conditions that arise from errors in the genetic makeup of cells either congenital diseases resulting from a deletion or mutation in a gene or malignant diseases where genetic regulation mechanisms have been deranged. Suicide gene therapy is one of several gene therapeutic approaches to treat cancer. READ MORE