Search for dissertations about: "HYPOXIC"

Showing result 1 - 5 of 210 swedish dissertations containing the word HYPOXIC.

  1. 1. Hypoxic pulmonary vasoconstriction and nitric oxide

    Author : Kristina Hambraeus Jonzon; Karolinska Institutet; Karolinska Institutet; []
    Keywords : hypoxia; pulmonary vasoconstriction; regional pulmonary bloodflow; stimulus-response; nitric oxide; blood-borne distant effects; nitric oxide synthase activity; inhaled; exhaled; non-enzymatic;

    Abstract : Hypoxia causes pulmonary vasoconstriction (HPV), improving oxygenation by redistribution of the pulmonary blood flow to better oxygenated lung regions. HPV is intrinsic to the pulmonary vascular smooth muscle cell, but can be modulated by several vasoactive substances, as for example endothelium derived nitric oxide (NO) and endothelin-1 (ET-1). READ MORE

  2. 2. Birth asphyxia : Fetal scalp blood sampling and risk factors for hypoxic ischemic encephalopathy

    Author : Lena Liljeström; Maria Jonsson; Anna-Karin Wikström; Ulf Högberg; Andreas Herbst; Uppsala universitet; []
    Keywords : asphyxia; fetal scalp blood sampling; hypoxic ischemic encephalopathy; obstetric emergencies; operative deliveries for fetal distress; overweight; short stature; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Preventing birth asphyxia is a major challenge in delivery care. The aims of this thesis were to evaluate fetal scalp blood sampling (FBS) and explore risk factors for moderate to severe neonatal hypoxic ischemic encephalopathy (HIE). READ MORE

  3. 3. Neonatal hypoxic ischemic encephalopathy : inflammation and therapies

    Author : Elena Di Martino; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Neonatal hypoxic ischemia (HI) is a severe condition characterized by a complex pathophysiology. The lack of oxygen (hypoxia) and blood flow (ischemia) leads to neuronal cell death via necrosis and apoptosis, and a consequent post-ischemic inflammation. HI brain injury may lead to seizures, cognitive and motor impairments, and death. READ MORE

  4. 4. Volatile anesthetic agents and hypoxic ventilatory responses in humans

    Author : Dick Sjögren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : anesthesia; volatile; isoflurane; sevoflurane; isocapnia; poikilocapnia; human; hypoxic ventilatory response;

    Abstract : Control of breathing in humans is regulated through a network of different nervous and chemical mechanisms, in the central nervous system as well as in peripheral structures. One important stimulus for this control is the decrease in arterial oxygen tension, PaO2, in blood, which leads to an increased ventilation. READ MORE

  5. 5. Hypoxic ischemic encephalopathy : diagnosis, hypothermia treatment and outcome

    Author : Boubou Hallberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hypothermia treatment (HT) is now proven to be neuroprotective, is associated with favourable outcomes, and is considered as the standard of care for moderate to severe hypoxic ischemic encephalopathy (HIE). The treatment should be regionalized with a minimum of ten treated infants per year with regard to securing patient safety, staff training, development and future research. READ MORE