Search for dissertations about: "Hanna Hedman"

Found 1 swedish dissertation containing the words Hanna Hedman.

2. 1. Nucleic Acids as Drugs and Drug Targets With Focus on Anticancer Active Platinum Complexes and Small Interfering RNAs

   Author : Hanna Hedman; Biokemi och Strukturbiologi; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Anticancer drugs; platinum complexes; cisplatin; oxaliplatin; nucleic acid; RNA; DNA; siRNA; thermodynamic stability; mass spectrometry; MALDI-MS; chemical probing; luciferase assay;

   Abstract : To ensure that patients receive a safe and effective treatment, it is important to understand how drugs interact with and affect molecules within a cell. Here, evaluation of platinum based drugs and their ability to interfere with nucleic acid functions is presented. READ MORE