Search for dissertations about: "Haplotypes"

Showing result 6 - 10 of 158 swedish dissertations containing the word Haplotypes.

  2. 6. MHC polymorphism in a songbird : Fitness, mate choice, and sexual conflict

    Author : Jacob Roved; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Major histocompatibility complex; MHC diversity; MHC haplotypes; sexually antagonistic selection; costs of immune responses; adaptive immunity; great reed warbler; songbird;

    Abstract : Sex differences in immune responses have been observed across a wide range of animal species, with the generaltendency that males have weaker immune responses than females. These differences are at least partly caused by immune-regulating effects of sex hormones, and have been associated with an increased prevalence of autoimmune disorders in females and with a general tendency for males to be parasitized more often than females. READ MORE

  4. 7. Autoantibodies as markers of beta-cell autoimmunity in children

    Author : Hanna Holmberg; Johnny Ludvigsson; Mona Landin-Olsson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Autoantibodies; Beta-cell autoimmunity; Children; Breast-feeding; HLA haplotypes; Insulin gene; Paediatric medicine; Pediatrisk medicin;

    Abstract : Type 1 diabetes (T1D) is a chronic disease caused by destruction of the insulin producing beta-cells in the pancreas. The incidence of T1D has increased rapidly, especially in the Western world and among young children. READ MORE

  5. 8. Intra-specific variation in avian malaria : Linking infection dynamics to haplotypes

    Author : Victor Kalbskopf; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; avian malaria; phyogenetics; population genetics; evolution;

    Abstract : Avian Malaria infects thousands of species of birds across the Aves class. The most widespread (geographically and phylogenetically)morphological species is Plasmodium relictum, and of that, the mitochondrial lineage of SGS1 is the most common and invasive. READ MORE

  6. 9. Fibrinogen and susceptibility to myocardial infarction : role of gene-gene and gene-environment interactions

    Author : Maria Nastase Mannila; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Atherothrombosis; epistasis; fibrinogen; fibrinogen gamma; fibrin clot structure; haplotypes; myocardial infarction; pleiotropy; SNPs;

    Abstract : Fibrinogen, the precursor of fibrin, is a glycoprotein synthesized in the liver and maintained in plasma at concentrations normally ranging between 2-4 g/L. The fibrinogen molecule consists of two sets of three non-identical polypeptide chains, which are encoded by the fibrinogen gamma (FGG), fibrinogen alpha (FGA) and fibrinogen beta (FGB) genes clustered on chromosome 4. READ MORE

  7. 10. Genes of the serotonergic system and susceptibility to psychiatric disorders : a gene-based haplotype approach

    Author : Ghazal Zaboli; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Borderline Personality Disorder; Candidate genes; Case-control; Depression; Gene-based haplotypes; Linkage Disequilibrium; Schizophrenia; SNP.;

    Abstract : Psychiatric disorders are complex, non-mendelian disorders. Complex disorders are ultimately determined by a number of genetic and environmental factors, and the effect of each factor may be obscured or confounded by others. READ MORE