Search for dissertations about: "Harald Kolmar"
Found 4 swedish dissertations containing the words Harald Kolmar.
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1. Combinatorial Protein Engineering Of Affibody Molecules Using E. Coli Display And Rational Design Of Affibody-Based Tracers For Medical Imaging
Abstract : Directed evolution is today an established strategy for generation of new affinity proteins. This thesis describes the development of a cell-display method using Escherichia coli for directed evolution of Affibody molecules. READ MORE
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2. Targeting HER2-expressing tumors with potent drug conjugates and fusion toxins based on scaffold proteins
Abstract : Targeted therapy is an emerging treatment for a variety of cancers. Small- sized scaffold proteins are an alternative to conventional antibody-based targeting molecules. READ MORE
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3. Chemical Synthesis of Affibody Molecules for Protein Detection and Molecular Imaging
Abstract : Proteins are essential components in most processes in living organisms. The detection and quantification of specific proteins can be used e.g. as measures of certain physiological conditions, and are therefore of great importance. READ MORE
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4. Bacterial display systems for engineering of affinity proteins
Abstract : Directed evolution is a powerful method for engineering of specific affinity proteins such as antibodies and alternative scaffold proteins. For selections from combinatorial protein libraries, robust and high-throughput selection platforms are needed. READ MORE