Search for dissertations about: "Health and drug"

Showing result 1 - 5 of 1382 swedish dissertations containing the words Health and drug.

  1. 1. Intracellular unbound drug concentrations : Methodology and application for understanding cellular drug exposure

    Author : André Mateus; Per Artursson; Pär Matsson; José A. G. Morais; Jeff Krise; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracellular unbound drug concentrations; free drug; drug binding; drug transport; drug accumulation; cellular drug response; drug target engagement; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Most known drug targets and metabolizing enzymes are located inside cells. Interactions with these proteins are determined by intracellular unbound drug concentrations. Assessing intracellular drug exposure is technically challenging, but essential for predicting pharmacokinetic, pharmacological, and toxicological profiles of new drugs. READ MORE

  2. 2. Health and People with Usher syndrome

    Author : Moa Wahlqvist; Berth Danermark; Claes Möller; Kerstin Möller; Elina Mäki-Torkko; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Usher syndrome; Deafblindness; Health; General Health; Physical Health; Psychological Health; Social Trust; Financial Situation; Handikappvetenskap; Disability Research;

    Abstract : The present thesis concerns people with Usher syndrome (USH) and their health. People with USH have a congenital hearing loss of various degrees and an eye disease with a progressive course; for some, the balance is also affected. Three clinical groups have been identified 1, 2 and 3, and 13 genes have currently been identified. READ MORE

  3. 3. Swedish Pharmaceutical Benefit Reforms ?Analyses of implementation, pharmaceutical sales patterns and expenditures

    Author : Karolina Andersson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmaceutical policy; health care reform; reimbursement; co-payment; reference-based pricing; generic substitution; drug cost; cost sharing;

    Abstract : Background: Over the last few decades, the sales of prescription drugs have increased dramatically in many western countries; however, this increase requires individuals and society to bear larger economic consequences. To improve cost control for pharmaceuticals, several reforms attempt to reconcile the economic responsibility of the patients, prescribers and third party payers. READ MORE

  4. 4. The health condition in the Sami population of Sweden, 1961-2002 : Causes of death and incidences of cancer and cardiovascular diseases

    Author : Sven Hassler; Per Sjölander; Peter Bjerregaard; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; Sami; Health; Epidemiology; Reindeer herder; Cardiovascular diseases; Cancer; Causes of death; Acculturation; Sweden; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; epidemiologi; Epidemiology;

    Abstract : The Sami people are the Natives of northern Scandinavia. The knowledge of the health and living conditions of the Swedish Sami is extremely limited which is in contrast to the large amount of detailed information on health and socioeconomic issues that is available for other circumpolar Natives. READ MORE

  5. 5. Improving efficiency, access to and quality of the rural health extension programme in Tigray, Ethiopia : the case of malaria diagnosis and treatment

    Author : Hailemariam Lemma; Miguel San Sebastian; Curt Löfgren; Wakgari Deressa; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Health extension programme; Malaria; Rapid diagnostic test; Acess health care; Efficiency; Cost-effectiveness; Adherence; Community health worker.; folkhälsa; Public health;

    Abstract : Introduction: Ensuring universal access to primary health care (PHC) is a key component of the Ethiopian nationalhealth policy. The policy also emphasises promoting and enhancing national self-reliance in health development bymobilizing and efficiently utilizing resources including community participation. READ MORE