Search for dissertations about: "Heart tumor"
Showing result 1 - 5 of 34 swedish dissertations containing the words Heart tumor.
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1. Heart Regeneration : Lessons from the Red Spotted Newt
Abstract : Unlike mammals, adult salamanders possess an intrinsic ability to regenerate complex organs and tissue types, making them an exciting and useful model to study tissue regeneration. The aims of this thesis are two fold, (1) to develop and characterize a reproducible cardiac regeneration model system in the newt, and (2) to decipher the cellular and molecular underpinnings involved in regeneration. READ MORE
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2. The role of Shb in ES cell differentiation, angiogenesis and tumor growth
Abstract : Shb is a ubiquitously expressed adaptor protein with the ability to bind several tyrosine kinase receptors and intracellular signaling proteins. Previous studies have implied a wide spectrum of Shb-mediated cellular responses, which motivated me to further investigate the role of Shb in differentiation and angiogenesis. READ MORE
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3. Pathophysiological role and clinical relevance of cytokines in hypertensive heart failure. A combined clinical and experimental study
Abstract : Although mortality due to heart failure has decreased significantly in the last decade since the introduction of ACE-inhibitors and ?-adrenergic receptor blockers in the management of heart failure, chronic heart failure is still one of the most important causes of morbidity and mortality and has a very high frequency for readmission to hospitalization because of the aggravation of heart failure. This accounts for a significantly higher health-care expenditure that is twice as much the cost for cancer. READ MORE
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4. Towards Immunotherapy of Midgut Carcinoid Tumors
Abstract : Classical midgut carcinoids belong to neuroendocrine tumors of the gastroenteropancreatic tract (GEP-NETs) and are associated with serotonin overproduction. The term midgut is derived from the tumors’ embryological site of origin: enterochromaffin cells in the lower jejunum, ileum, caecum and the ascending colon. READ MORE
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5. Studies on Redox-proteins and Cytokines in inflammation and Cancer
Abstract : The redox state in the cell plays a major role in determining vital functions and its major imbalance can lead to severe cell injury or death. Redox active proteins and cytokines involved in this process includes thioredoxin (Trx), protein disulfide isomerase (PDI), and tumor necrosis factor (TNF) superfamilies. READ MORE