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Found 1 swedish dissertation matching the above criteria.

  1. 1. Mechanisms of phagocytosis resistance in Streptococcus pyogenes

    Author : Heike Kotarsky; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; fibrinogen; FHL-1; Factor H; M protein; Streptococcus pyogenes; phagocytosis;

    Abstract : A distinguishing feature of Streptococcus pyogenes (GAS) is their ability to resist phagocytosis in whole human blood in the absence of type-specific antibodies, a property that is dependent on the expression of the surface associated M proteins. A common characteristic of M proteins is their interaction with a variety of host proteins including the complement regulatory protein factor H (FH) and fibrinogen that plays a key role in coagulation. READ MORE