Search for dissertations about: "Helena Brändström"

Found 2 swedish dissertations containing the words Helena Brändström.

  2. 1. Osteoprotegerin in Bone Metabolism

    Author : Helena Brändström; Uppsala universitet; []
    Keywords : Medical sciences; Bone; osteoprotegerin; osteoblasts; polymorphism; cytokines; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Bone turnover, remodeling, is a constant process replacing old bone with new. This complex cellular event involves resorption by osteoclasts and formation of new bone by osteoblasts. The balance between osteoblastic and osteoclastic activity is under regulation by several endocrine and paracrine factors. READ MORE

  4. 2. Genetic Variability in Human Bone Phenotypes : The Vitamin D Receptor Gene and the Estrogen Receptor-α Cofactor RIZ Gene

    Author : Elin Grundberg; Andreas Kindmark; Östen Ljunggren; Helena Brändström; André G. Uitterlinden; Uppsala universitet; []
    Keywords : Medicine; Bone mineral density; candidate gene approach; polymorphism; the vitamin D receptor; the estrogen receptor α; RIZ1; cofactor; allelic imbalance; Medicin;

    Abstract : Important candidate genes to human bone phenotypes are those involved in the regulation of hormonal action, such as the vitamin D receptor (VDR) and the estrogen receptor-α (ERα) genes and their cofactors. RIZ1 is a specific ERα cofactor proved to strongly enhance the function of the ERα. READ MORE