Search for dissertations about: "Helin Vakifahmetoglu"

Found 1 swedish dissertation containing the words Helin Vakifahmetoglu.

2. 1. DNA damage-induced cell death : the role of caspase-2

   Author : Helin Vakifahmetoglu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Apoptosis; caspase-2; DNA damage; mitotic catastrophe; p53;

   Abstract : Activation of a family of cysteine proteases, called caspases, is an important event during apoptosis. In comparison to other caspases, less is known about regulatory functions of caspase-2. Previous studies from our group established caspase-2 as an essential apical regulator of apoptosis triggered by DNA damage. READ MORE