Search for dissertations about: "Hematopoietic Stem Cell"

Showing result 6 - 10 of 246 swedish dissertations containing the words Hematopoietic Stem Cell.

  2. 6. Consequences of Shb Deficiency on Hematopoietic Cell Function

    Author : Karin Gustafsson; Michael Welsh; Martin Bergö; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hematopoiesis; hematopoietic stem cells; myeloid neoplasia; T cells; atopic dermatitis; cell signaling; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : The adaptor protein Shb has been implicated in the signaling of several tyrosine kinase receptors and previous studies have suggested a role for Shb in the signal transduction of T cells. Shb associates with the T cell receptor (TCR) and partakes in the signal propagation of activated T lymphocytes. READ MORE

  4. 7. Cellular and Molecular Pathways Governing Hematopoietic Stem Cell Fate

    Author : Liping Yang; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stem cell; hematopoiesis; bone marrow transplantation; lineage commitment; cytokine; Medicine human and vertebrates ; Clinical genetics; Klinisk genetik; extracellulära vätskor; Hematologi; Medicin människa och djur ; extracellular fluids; Haematology;

    Abstract : Hematopoietic Stem Cells (HSCs) have been defined to have abilities of both self-renewal and multi-lineage differen-tiation. The balance between these abilities is rigorously controlled under steady-state status (homeostasis) and when the normal processes of self-renewal and differentiation become deregulated, a disorder of blood system (such as leukemias) can occur. READ MORE

  5. 8. Exploring the heterogeneity of the hematopoietic stem and progenitor cell pool in cord blood

    Author : Sofia Frändberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cord blood; Cord blood bank; Cord clamping; Hematopoietic stem cell transplantation; Hematopoietic stem and progenitor cells; CD34; Side Population; Aldehyde dehydrogenase; Apoptosis; CDCP1;

    Abstract : Hematopoietic stem cell transplantation (HSCT) is a curative treatment for a wide range of malignant and hereditary disorders. It is yet the only clinically established stem cell treatment. READ MORE

  6. 9. Molecular regulation of hematopoietic stem cells

    Author : David Bryder; Avdelningen för molekylär hematologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; extracellular fluids; Haematology; bone marrow transplantation; cytokines; Hematopoiesis; stem cells;

    Abstract : Hematopoietic stem cells (HSCs) are ultimately responsible for the all mature blood cell production. They can primarily be found in the bone marrow (BM) at a low frequency (~0.02%). READ MORE

  7. 10. Molecular Mechanisms in Hematopoietic Stem Cell Aging

    Author : Gudmundur Norddahl; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The blood is composed of many different cell types that through tightly regulated mechanisms are derived from hematopoietic stem cells (HSCs). In addition, HSCs are able to undergo self-renewing divisions whereby new HSCs are produced. READ MORE